3-(2-氧代环十二烷基)丙腈合成路线 （共 9 条）
反应条件
hydrogenchloride; acetic acid 8 h; Heating;
参考文献
Zakharkin, L. I.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 10 p. 1895 - 1899
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 10 p. 2146 - 2150
反应条件
1: 94 percent / H2 / RaNi / ethanol / 5 h / 120 °C / 53200 Torr 2: 96 percent / 10percent PdC / 0.5 h / 250 - 300 °C View Scheme
参考文献
Zakharkin, L. I.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 10 p. 1895 - 1899
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 10 p. 2146 - 2150
反应条件
cyclohexylamine; acetic acid; hydroquinone
T=120 - 200°C;
参考文献
Zakharkin, L. I.; Churilova, I. M.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 10 p. 1895 - 1899
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 10 p. 2146 - 2150
反应条件
1: 92 percent / toluene-p-sulphonic acid / benzene / 20 h / Heating
2: 2) acetic acid / 1) MeOH, 17 h, reflux 2) 1 h, reflux
View Scheme
参考文献
Hickmott, Peter W.; Jutle, Kasturi K.; Pienar, Daniel H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 9 p. 2399 - 2402
反应条件
acetic acid
1) MeOH, 17 h, reflux 2) 1 h, reflux; Yield given. Multistep reaction;
参考文献
Hickmott, Peter W.; Jutle, Kasturi K.; Pienar, Daniel H.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 9 p. 2399 - 2402
反应条件
(i) DBN, (ii) LiI, 2,4,6-collidine; Multistep reaction;
参考文献
Bailey,A.S. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 259 - 265
反应条件
1: 4 percent / Et4NOTs / propan-2-ol / 65 °C / electroreduction (Sn-cathode)
2: 83 percent / p-TsOH / benzene / 2 h / Heating
View Scheme
参考文献
Shono, Tatsuya; Kise, Naoki; Fujimoto, Taku; Tominaga, Naoto; Morita, Hiroshi
Journal of Organic Chemistry, 1992 , vol. 57, # 28 p. 7175 - 7187
反应条件
ammonium acetate; cyanoacetic acid ethyl ester in benzene
参考文献
Bailey,A.S. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 259 - 265
参考文献
Bailey,A.S. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 259 - 265
