2,3-二氢-6-甲氧基-1H-茚-1-乙酸合成路线 （共 6 条）
反应条件
water; sodium hydroxide in methanol
T=20°C; 3 h;
参考文献
Hegde, Vinayak; Campitelli, Marc; Quinn, Ronald J.; Camp, David
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 12 p. 4570 - 4579
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.83 h / 0 - 20 °C / Inert atmosphere
1.2: 16 h / 0 °C / Reflux
1.3: 8 h / 50 °C
2.1: water; sodium hydroxide / methanol / 3 h / 20 °C
View Scheme
参考文献
Hegde, Vinayak; Campitelli, Marc; Quinn, Ronald J.; Camp, David
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 12 p. 4570 - 4579
反应条件
hydrogenchloride; Zn–Hg amalgam in benzene
Heating;
参考文献
Pramanik; Mukherjee
Journal of the Indian Chemical Society, 1997 , vol. 74, # 9 p. 734 - 735
反应条件
1: polyphosphoric acid / Heating
2: zinc amalgam, aq. HCl / benzene / Heating
View Scheme
参考文献
Pramanik; Mukherjee
Journal of the Indian Chemical Society, 1997 , vol. 74, # 9 p. 734 - 735
反应条件
1: piperidine / 72 h / 30 - 40 °C
2: KOH / ethanol / Heating
3: polyphosphoric acid / Heating
4: zinc amalgam, aq. HCl / benzene / Heating
View Scheme
参考文献
Pramanik; Mukherjee
Journal of the Indian Chemical Society, 1997 , vol. 74, # 9 p. 734 - 735
反应条件
1: 95 percent / SOCl2, NH3
2: 78 percent / P2O5 / Heating
3: 75 percent / NaN3, NH4Cl / dimethylformamide / 120 - 150 °C
View Scheme
参考文献
Roy, A.; Gupta, J. K.; Lahiri, S.C.
Journal of the Indian Chemical Society, 1983 , vol. 60, p. 377 - 380
