2-(2-噻吩基)-色原酮合成路线 （共 13 条）
反应条件
pyrrolidine; iodine in dimethyl sulfoxide
T=150°C; 6 h;
参考文献
Naik, Mayuri M.; Tilve, Santosh G.; Kamat, Vijayendra P.
Tetrahedron Letters, 2014 , vol. 55, # 22 p. 3340 - 3343
反应条件
iodine
T=100 - 110°C; 2.4 h; Neat (no solvent);
参考文献
Sashidhara, Koneni V.; Kumar, Manoj; Kumar, Abdhesh
Tetrahedron Letters, 2012 , vol. 53, # 18 p. 2355 - 2359
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; (Me)CgPPh in tetrahydrofuran; N,N-dimethyl-formamide
T=90°C; microwave-assisted Sonogashira-carbonylation-cyclization reaction; P=760.051 Torr; 0.5 h; Microwave irradiation;
参考文献
Awuah, Emelia; Capretta, Alfredo
Organic Letters, 2009 , vol. 11, # 15 p. 3210 - 3213
反应条件
copper(l) iodide; oxygen
T=50°C; oxa-Michael-oxidation; P=760.051 Torr; 48 h; Ionic liquid;
参考文献
Du, Zhiyun; Ng, Huifen; Zhang, Kun; Zeng, Huaqiang; Wang, Jian
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 20 p. 6930 - 6933
反应条件
diethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride
T=120°C; P=14710.2 Torr; 2 h;
参考文献
Torii, Sigeru; Okumoto, Hiroshi; Xu, Long He; Sadakane, Masahiro; Shostakovsky, Michel V.; Ponomaryov, Andrew B.; Kalinin, Valery N.
Tetrahedron, 1993 , vol. 49, # 31 p. 6773 - 6784
反应条件
palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide
T=120°C; P=3750.38 Torr; 16 h; Autoclave;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Chemistry - A European Journal, 2012 , vol. 18, # 40 p. 12595 - 12598
反应条件
1: 4-oxo-4H-1-benzopyran With (2,2,6,6-tetramethylpiperidine)2Zn·2MgCl2·2LiCl in tetrahydrofuran
T=-30°C; 1 h; Inert atmosphere;
2: 2-Iodothiophene With bis(dibenzylideneacetone)-palladium(0); P(2-furyl)3 in tetrahydrofuran
T=25°C; Negishi cross-coupling reaction; 1 h; Inert atmosphere; regioselective reaction;
参考文献
Klier, Lydia; Bresser, Tomke; Nigst, Tobias A.; Karaghiosoff, Konstantin; Knochel, Paul
Journal of the American Chemical Society, 2012 , vol. 134, # 33 p. 13584 - 13587
反应条件
water
T=110 - 115°C; 2 h;
参考文献
Vimal, Manorama; Pathak, Uma; Mathur, Sweta; Pandey, Lokesh Kumar; Suryanarayana
Heterocyclic Communications, 2010 , vol. 16, # 2-3 p. 151 - 154
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in diethylamine
T=120°C; P=15200 Torr; 2 h;
参考文献
Kalinin; Shostakovsky; Ponomaryov
Tetrahedron Letters, 1990 , vol. 31, # 28 p. 4073 - 4076
反应条件
thiophosphoryl trichloride; water; triethylamine
T=30 - 80°C; 0.333333 h;
参考文献
Vimal, Manorama; Pathak, Uma; Pandey, Lokesh Kumar; Suryanarayana, Malladi V. S.
Synthesis, 2011 , # 1 p. 30 - 32
