3-氨基-2-氯吡啶合成路线

240815-49-0咪唑并[1,5-a]吡啶并[3,2-e]吡嗪-6(5H)-酮

参考文献

Chen, Ping; Doweyko, Arthur M.; Norris, Derek; Gu, Henry H.; Spergel, Steven H.; Das, Jagabundhu; Moquin, Robert V.; Lin, James; Wityak, John; Iwanowicz, Edwin J.; McIntyre, Kim W.; Shuster, David J.; Behnia, Kamelia; Chong, Saeho; De Fex, Henry; Pang, Suhong; Pitt, Sydney; Shen, Ding Ren; Thrall, Sara; Stanley, Paul; Kocy, Octavian R.; Witmer, Mark R.; Kanner, Steven B.; Schieven, Gary L.; Barrish, Joel C.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 18 p. 4517 - 4529

1072-98-62-氨基-5-氯吡啶+

6298-19-73-氨基-2-氯吡啶+

201230-82-2

280115-74-4

参考文献

ELI LILLY AND COMPANY
Patent: WO2005/49604 A2, 2005 ;
Location in patent: Page/Page column 45 ;
WO 2005/049604 A2

6298-19-73-氨基-2-氯吡啶

781649-86-34-(2-氨基吡啶-3-基氨基)哌啶-1-羧酸叔丁酯

参考文献

Leahy, David K.; Desai, Lopa V.; Deshpande, Rajendra P.; Mariadass, Antony V.; Rangaswamy, Sundaramurthy; Rajagopal, Santhosh K.; Madhavan, Lakshmi; Illendula, Shashidhar
Organic Process Research and Development, 2012 , vol. 16, # 2 p. 244 - 249

6298-19-73-氨基-2-氯吡啶

781649-87-44-(2-氧代-2,3-二氢-1H-咪唑并[4,5-b]吡啶-1-基)哌啶-1-羧酸叔丁酯

参考文献

Leahy, David K.; Desai, Lopa V.; Deshpande, Rajendra P.; Mariadass, Antony V.; Rangaswamy, Sundaramurthy; Rajagopal, Santhosh K.; Madhavan, Lakshmi; Illendula, Shashidhar
Organic Process Research and Development, 2012 , vol. 16, # 2 p. 244 - 249

6298-19-73-氨基-2-氯吡啶+

134-20-3邻氨基苯甲酸甲酯

885-70-15,11-二氢-6H-吡啶并[2,3-B][1,4]苯并二氮杂-6-酮

参考文献

Journal of Heterocyclic Chemistry, , vol. 35, # 3 p. 675 - 686

6298-19-73-氨基-2-氯吡啶+

87-25-22-氨基苯甲酸乙酯

885-70-15,11-二氢-6H-吡啶并[2,3-B][1,4]苯并二氮杂-6-酮

参考文献

Journal of Medicinal Chemistry, , vol. 32, # 8 p. 1718 - 1724

6298-19-73-氨基-2-氯吡啶+

75-07-0乙醛

272-49-14-氮杂吲哚

参考文献

Fontan, Rafael; Galvez, Carmen; Viladoms, Pere
Heterocycles, 1981 , vol. 16, # 9 p. 1473 - 1474

6298-19-73-氨基-2-氯吡啶

78607-36-02-氯-3-碘吡啶

参考文献

Kuethe, Jeffrey T.; Wong, Audrey; Davies, Ian W.
Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7752 - 7754

6298-19-73-氨基-2-氯吡啶

52200-48-33-溴-2-氯吡啶

参考文献

DAIICHI SANKYO COMPANY, LIMITED; Kawanami, Koutarou
Patent: US2013/144061 A1, 2013 ;
Location in patent: Paragraph 0229; 0230 ;

6298-19-73-氨基-2-氯吡啶

7689-62-52-氯-1,5-萘啶

参考文献

FUJIFILM Corporation; FURUYAMA, Hidetomo; KURIHARA, Hideki; FURUYA, Kentarou; TERAO, Takahiro; SEKINE, Shinichirou; NAKAGAWA, Daisuke
Patent: EP2727920 A1, 2014 ;