1-(4-甲氧基苯基)乙胺合成路线 （共 45 条）
反应条件
1.1: NaH / dimethylformamide / 2 h / 0 °C 1.2: 80 percent / dimethylformamide / 4 h / 0 - 20 °C 2.1: BH3*THF; (S)-proline (R)-1,1'-bi(2-naphthyl)dioxyboryl ester / tetrahydrofuran / 48 h / 0 - 5 °C 2.2: aq. HCl / tetrahydrofuran View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 10 p. 3998 - 4001
反应条件
samarium diiodide; hydrogen; 1.) <(COD)Rh(1,2-bis((2R,5R)-2,5-diethylphospholano)-benzene)>+CF3SO3- 1.) 0 deg C, 12 h, isopropanol, 60 psi; 2.) methanol, THF, 30 min; Multistep reaction. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 50, # 15 p. 4399 - 4428
反应条件
coated protease in 3-methyl pentan-3-ol T=21°C; 48 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 9 p. 1759 - 1764
反应条件
water; hydroxide Title compound not separated from byproducts;
参考文献
Chemical Communications, , # 21 p. 2415 - 2416
反应条件
2: 2) Pb(OAc)4 / 1) THF, reflux, 2) CH2Cl2, MeOH View Scheme
参考文献
Journal of Organic Chemistry, , vol. 56, # 3 p. 1340 - 1344
反应条件
Chromobacterium violaceum ω-transaminase variant W60C T=37°C; pH=7; 12 h; Reagent/catalystpH-value; enantioselective reaction;
参考文献
Chemical Communications, , vol. 49, # 2 p. 161 - 163
反应条件
lead(IV) acetate 1) THF, reflux, 2) CH2Cl2, MeOH; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 56, # 3 p. 1340 - 1344
反应条件
Yield given. Multistep reaction;
参考文献
Chemical Communications, , # 2 p. 173 - 174
反应条件
triethylamine in dichloromethane T=20°C; 18 h;
参考文献
Wu, Yong-Jin; He, Huan; Sun, Li-Qiang; L'Heureux, Alexandre; Chen, Jie; Dextraze, Pierre; Starrett Jr., John E.; Boissard, Christopher G.; Gribkoff, Valentin K.; Natale, Joanne; Dworetzky, Steven I.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 11 p. 2887 - 2896
反应条件
in 3-methyl pentan-3-ol
参考文献
Queyroy, Severine; Vanthuyne, Nicolas; Gastaldi, Stephane; Bertrand, Michele P.; Gil, Gerard
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 9 p. 1759 - 1764
