(2-甲基-1H-吲哚-3-基)(氧代)乙酸甲酯合成路线 （共 6 条）
反应条件
1: 2-methyl-1H-indole; oxalyl dichloride in diethyl ether
T=0°C; Inert atmosphere;
2: methanol Inert atmosphere;
参考文献
Brieke, Clara; Heckel, Alexander
Chemistry - A European Journal, 2013 , vol. 19, # 46 p. 15726 - 15734
反应条件
in diethyl ether
T=0 - 20°C; Inert atmosphere;
参考文献
Liu, Chuan; Zhang, Wei; Dai, Li-Xin; You, Shu-Li
Organic Letters, 2012 , vol. 14, # 17 p. 4525 - 4527
反应条件
1: diethyl ether / 6 h / 0 - 20 °C / |Inert atmosphere
2: diethyl ether / 0 - 20 °C / |Inert atmosphere
View Scheme
参考文献
Liu, Chuan; Zhang, Wei; Dai, Li-Xin; You, Shu-Li
Organic Letters, 2012 , vol. 14, # 17 p. 4525 - 4527
参考文献
Giua
Gazzetta Chimica Italiana, 1924 , vol. 54, p. 595
Atti Congr. naz. Chim. ind., 1924 , p. 268
Chem. Zentralbl., 1925 , vol. 96, # I p. 2309
反应条件
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 20 °C
2.1: 1H-imidazole / N,N-dimethyl-formamide / 3 h / 0 - 20 °C
3.1: sodium hydride / tetrahydrofuran; mineral oil / 1.25 h / 0 - 20 °C
3.2: 20 °C
4.1: tetrabutyl ammonium fluoride / 24 h
View Scheme
参考文献
Han, Long; Liu, Chuan; Zhang, Wei; Shi, Xiao-Xin; You, Shu-Li
Chemical Communications, 2014 , vol. 50, # 10 p. 1231 - 1233
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=0 - 80°C; 2 h; Inert atmosphere;
参考文献
Han, Long; Liu, Chuan; Zhang, Wei; Shi, Xiao-Xin; You, Shu-Li
Chemical Communications, 2014 , vol. 50, # 10 p. 1231 - 1233
