槟榔碱合成路线 - 魔法化学

参考文献

Nopco Chem. Co.
Patent: US2569182 , 1949 ;

63-75-2槟榔碱+

580-13-22-溴代萘+

106-93-4二溴乙烷

265112-64-9(3S,4s)-1-甲基-4-(萘-2-基)哌啶-3-羧酸甲酯

参考文献

Georgetown University
Patent: US6440996 B1, 2002 ;

63-75-2槟榔碱

265112-64-9(3S,4s)-1-甲基-4-(萘-2-基)哌啶-3-羧酸甲酯

参考文献

Tamiz, Amir P.; Zhang, Jianrong; Flippen-Anderson, Judith L.; Zhang, Mei; Johnson, Kenneth M.; Deschaux, Olivier; Tella, Srihari; Kozikowski, Alan P.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 6 p. 1215 - 1222

63-75-2槟榔碱

215725-59-03,6-二氢-1,3(2H)-吡啶二甲酸 1-叔丁酯 3-甲酯

参考文献

Long, Sha; Stefani, Francesca Romana; Biondi, Stefano; Ghiselli, Giancarlo; Panunzio, Mauro
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5811 - 5822

63-75-2槟榔碱+

105-45-3乙酰乙酸甲酯

75690-06-1

参考文献

Coffen, David L.; Hengartner, Urs; Katonak, David A.; Mulligan, Mary E.; Burdick, David C.; et al.
Journal of Organic Chemistry, 1984 , vol. 49, # 26 p. 5109 - 5113

63-75-2槟榔碱

86447-15-61-甲基-1,,3,6-四氢吡啶-3-羧酸甲酯

参考文献

Jakobsen, Palle; Lundbeck, Jane M; Kristiansen, Marit; Breinholt, Jens; Demuth, Helle; Pawlas, Jan; Torres Candela, Maria P; Andersen, Birgitte; Westergaard, Niels; Lundgren, Karsten; Asano, Naoki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 733 - 744

63-75-2槟榔碱

88928-69-21-苄基-1,2,5,6-四氢吡啶-3-羧酸甲酯

参考文献

Long, Sha; Stefani, Francesca Romana; Biondi, Stefano; Ghiselli, Giancarlo; Panunzio, Mauro
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 18 p. 5811 - 5822

63-75-2槟榔碱

495-19-21,2,5,6-四氢吡啶-3-羧酸甲酯

参考文献

Jakobsen, Palle; Lundbeck, Jane M; Kristiansen, Marit; Breinholt, Jens; Demuth, Helle; Pawlas, Jan; Torres Candela, Maria P; Andersen, Birgitte; Westergaard, Niels; Lundgren, Karsten; Asano, Naoki
Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 3 p. 733 - 744

63-75-2槟榔碱

6197-39-3

参考文献

Rosenau, Thomas; Hofinger, Andreas; Potthast, Antje; Kosma, Paul
Organic Letters, 2004 , vol. 6, # 4 p. 541 - 544