1: With recombinant Alcaligenes faecalis penicillin G acylase immobilized on oxirane acrylic carrier; potassium hydroxide in water T=35°C; pH=10; 5.66667 h; Enzymatic reaction; 2: With hydrogenchloride in water pH=1; optical yield given as percent eeenantioselective reaction;
1: With recombinant Alcaligenes faecalis penicillin G acylase immobilized on oxirane acrylic carrier; potassium hydroxide in water T=35°C; pH=10; 5.66667 h; Enzymatic reaction; 2: With hydrogenchloride in water pH=1; optical yield given as percent eeenantioselective reaction;
1: With lithium hydroxide; dihydrogen peroxide in tetrahydrofuran; water T=20°C; Hydrolysis; 12 h; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; Hydrolysis; 24 h; Further stages.;
参考文献
Guillena; Najera
Journal of Organic Chemistry, 2000 , vol. 65, # 22 p. 7310 - 7322
