反应条件
1.1: sodium tetrahydroborate; iodine / tetrahydrofuran / Cooling with ice; Reflux 2.1: potassium carbonate / methanol; water / 0.17 h / Reflux 2.2: 1 h / Heating 3.1: sulfur trioxide pyridine complex; triethylamine / dimethyl sulfoxide / 1.08 h / 15 °C / Cooling with ice 4.1: lithium / tetrahydrofuran / 3 h / -65 °C / Inert atmosphere 5.1: palladium hydroxide on carbon; hydrogen / methanol / 4 h / 20 °C / 760.05 Torr 6.1: triethylamine / tetrahydrofuran / 20 °C / Cooling with ice View Scheme
参考文献
Shi, Lei; Chen, Liping; Chen, Ryan; Chen, Liqin
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 3 p. 148 - 152