6,6-二甲基二氢嘧啶-2,4(1h,3h)-二酮合成路线 （共 5 条）
反应条件
1: With sodium hydroxide 2: With hydrogenchloride
参考文献
Rachina, Vetka; Blagoeva, Iva
Synthesis, 1982 , # 11 p. 967 - 968
反应条件
hydrogenchloride; sodium hydroxide 1.) H2O, reflux, 1 h, 2.) H2O, 3.) dioxane, 12 h; Yield given. Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 79, # 8 p. 2043 - 2066
反应条件
in ethylene glycol
T=190°C; Michael addition; 1 h;
参考文献
Hughes, Andrew B.; Sleebs, Brad E.
Helvetica Chimica Acta, 2006 , vol. 89, # 11 p. 2611 - 2637
反应条件
hydrogenchloride
T=30.5 - 60°C; Kinetics;
参考文献
Blagoeva,I.B. et al.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1979 , p. 1115 - 1122
反应条件
1.1: aq. NaOH
1.2: aq. HCl
2.1: Et3N / dimethylformamide
View Scheme
参考文献
Hughes, Andrew B.; Sleebs, Brad E.
Australian Journal of Chemistry, 2005 , vol. 58, # 11 p. 778 - 784
