反应条件
1: 83 percent / I2, 1,1,3,3-tetramethylguanidine / tetrahydrofuran; diethyl ether / 1 h 2: 2 M aq. Na2CO3 / bis(triphenylphosphine)palladium(II) chloride / tetrahydrofuran / 96 h / 80 °C View Scheme
参考文献
CRYSTAL PHARMA, S.A.U.; Perez Encabo, Alfonso; Turiel Hernandez, Jose Angel; Gallo Nieto, Francisco Javier; Lorente Bonde-Larsen, Antonio; Sandoval Rodriguez, Celso Miguel
Patent: US2014/11992 A1, 2014 ;