1,1,2-三苯基丁-1-烯合成路线 （共 16 条）
反应条件
oxygen; dimethyl sulfoxide; palladium diacetate
T=20°C; 24 h;
参考文献
Zhou, Chengxiang; Larock, Richard C.
Organic Letters, 2005 , vol. 7, # 2 p. 259 - 262
反应条件
potassium hydroxide; tetrabutyl-ammonium chloride; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
48 h; Heating;
参考文献
Shao, Li-Xiong; Shi, Min
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 10 p. 1828 - 1831
反应条件
1: 1-(benzyloxy)-4-iodo-1H-pyrazole; (Z)-2,2'-(1-phenylbut-1-ene-1,2-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) With potassium hydroxide; 3,5-dimethoxy-phenol; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether
T=20°C; Suzuki coupling reaction; 24 h;
2: iodobenzene With potassium hydroxide; 3,5-dimethoxy-phenol; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether
T=20°C; Suzuki coupling reaction; 24 h;
参考文献
Wenckens, Martin; Jakobsen, Palle; Vedso, Per; Huusfeldt, Per Olaf; Gissel, Birgitte; Barfoed, Marianne; Brockdorff, Bettina Lundin; Lykkesfeldt, Anne E.; Begtrup, Mikael
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 8 p. 1883 - 1899
反应条件
potassium hydrogensulfate
T=190°C;
参考文献
Dodds et al.
Proceedings of the Royal Society of London, Series B: Biological Sciences, 1945 , vol. 132, p. 83,95
反应条件
1: triphenylphosphine / 4 h / 60 °C
2: 2 percent / NiCl2(dppp) / tetrahydrofuran / 28 h / Heating
View Scheme
参考文献
Okamoto, Yuzo; Yoshikawa, Yutaka; Hayashi, Takatoshi
Journal of Organometallic Chemistry, 1989 , vol. 359, p. 143 - 150
反应条件
1: diethyl ether / 2 h / Heating
2: H2SO4, AcOH / 0.33 h / Heating
View Scheme
参考文献
Schneider, Martin R.; Angerer, Erwin von; Schoenenberger, Helmut; Michel, Ralf Th.; Fortmeyer, H. P.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1070 - 1077
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II) in tetrahydrofuran
28 h; Heating;
参考文献
Okamoto, Yuzo; Yoshikawa, Yutaka; Hayashi, Takatoshi
Journal of Organometallic Chemistry, 1989 , vol. 359, p. 143 - 150
反应条件
potassium fluoride; oxygen; palladium diacetate; propionic acid
T=20°C; Oxidative Heck reaction; 24 h; regioselective reaction;
参考文献
He, Zhiheng; Kirchberg, Sylvia; Froehlich, Roland; Studer, Armido
Angewandte Chemie - International Edition, 2012 , vol. 51, # 15 p. 3699 - 3702
反应条件
2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; palladium diacetate
T=100°C; Negishi coupling; Product distribution; Further Variations:ReagentsCatalystsTemperatures;
参考文献
Nunes, Carolina M.; Steffens, Daniela; Monteiro, Adriano L.
Synlett, 2007 , # 1 p. 103 - 106
反应条件
1: NaOEt / ethanol / 4.17 h / Heating
2: diethyl ether / 2 h / Heating
3: H2SO4, AcOH / 0.33 h / Heating
View Scheme
参考文献
Schneider, Martin R.; Angerer, Erwin von; Schoenenberger, Helmut; Michel, Ralf Th.; Fortmeyer, H. P.
Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1070 - 1077
