2-(2-环己烯)丙二酸二乙酯合成路线 （共 8 条）
反应条件
lithium chloride in water; dimethyl sulfoxide T=170°C; Decarboxylation; 24 h;
参考文献
Fernandez-Mateos, A.; Alonso, J. J. Perez; Gonzales, R. Rubio
Tetrahedron, 1999 , vol. 55, # 3 p. 847 - 860
反应条件
1: 100 percent / H2 / 10 percent Pd/C 2: 100 percent / LiAlH4 View Scheme
参考文献
Fraley, Mark E.; Hoffman, William F.; Rubino, Robert S.; Hungate, Randall W.; Tebben, Andrew J.; Rutledge, Ruth Z.; McFall, Rosemary C.; Huckle, William R.; Kendall, Richard L.; Coll, Kathleen E.; Thomas, Kenneth A.
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 19 p. 2767 - 2770
反应条件
hydrogen; palladium on activated charcoal
参考文献
Fraley, Mark E.; Hoffman, William F.; Rubino, Robert S.; Hungate, Randall W.; Tebben, Andrew J.; Rutledge, Ruth Z.; McFall, Rosemary C.; Huckle, William R.; Kendall, Richard L.; Coll, Kathleen E.; Thomas, Kenneth A.
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 19 p. 2767 - 2770
反应条件
1: 88 percent / NaCl / dimethylsulfoxide; H2O / 10 h / 170 °C 2: 85 percent / LiAlH4 / diethyl ether / 0.5 h 3: 90 percent / pyridine, trifluoroacetic acid, dicyclohexylcarbodiimide / benzene; dimethylsulfoxide / 24 h 4: 45 percent / ethanol / 4 h / 65 °C View Scheme
参考文献
Dzieduszycka, Maria; Smulkowski, Maciej; Borowski, Edward
Polish Journal of Chemistry, 1982 , vol. 56, # 10-12 p. 1569 - 1571
反应条件
1: 88 percent / NaCl / dimethylsulfoxide; H2O / 10 h / 170 °C
2: 85 percent / LiAlH4 / diethyl ether / 0.5 h
3: 90 percent / pyridine, trifluoroacetic acid, dicyclohexylcarbodiimide / benzene; dimethylsulfoxide / 24 h
View Scheme
参考文献
Dzieduszycka, Maria; Smulkowski, Maciej; Borowski, Edward
Polish Journal of Chemistry, 1982 , vol. 56, # 10-12 p. 1569 - 1571
反应条件
1: durch Verseifung
2: durch Destillation im Vakuum
View Scheme
参考文献
Julia,M. et al.
Bulletin de la Societe Chimique de France, 1964 , p. 1116 - 1122
反应条件
1: 88 percent / NaCl / dimethylsulfoxide; H2O / 10 h / 170 °C
2: 85 percent / LiAlH4 / diethyl ether / 0.5 h
View Scheme
参考文献
Youssef,A.A.; Sharaf,S.M.
Journal of Organic Chemistry, 1968 , vol. 33, # 6 p. 2581 - 2583
反应条件
lithium chloride in water; dimethyl sulfoxide
T=170°C; Decarboxylation; 24 h;
参考文献
Fernandez-Mateos, A.; Alonso, J. J. Perez; Gonzales, R. Rubio
Tetrahedron, 1999 , vol. 55, # 3 p. 847 - 860
