5-[(5-羧基-3-乙氧羰基-4-甲基-1H-吡咯-2-基)甲基]-4-乙氧羰基-3-甲基-1H-吡咯-2-羧酸合成路线 （共 5 条）
参考文献
Byun; Lightner
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1683 - 1692
参考文献
Andrews et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 491,493
反应条件
1: 42 percent / bromine / acetic acid / 0.5 h / 40 - 43 °C
2: 50 percent / aq. HBr / methanol / 7 h / Heating
3: NaOH / ethanol; H2O / 3 h / Heating
View Scheme
参考文献
Byun; Lightner
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1683 - 1692
反应条件
1: 50 percent / aq. HBr / methanol / 7 h / Heating
2: NaOH / ethanol; H2O / 3 h / Heating
View Scheme
参考文献
Byun; Lightner
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1683 - 1692
反应条件
potassium hydroxide
3 h; Heating;
参考文献
Brittain, Judith M.; Jones, R. Alan; Jones, Richard O.; King, Trevor J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2656 - 2661
