2-甲氧基-5-甲基苯甲酸甲酯合成路线 （共 24 条）
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane
Reflux;
参考文献
Zhi, Ying; Gao, Li-Xin; Jin, Yi; Tang, Chun-Lan; Li, Jing-Ya; Li, Jia; Long, Ya-Qiu
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 14 p. 3670 - 3683
反应条件
1: 87 percent / LiAlH4 / tetrahydrofuran / 20 h / Heating
2: 69 percent / thionyl chloride, pyridine / toluene / 24 h / Ambient temperature
3: 91 percent / KI / dimethylsulfoxide / 20 h / Ambient temperature
4: aq. NH3, Raney Ni / ethanol / 48 h / 40 - 50 °C
View Scheme
参考文献
Langlois, Michel; Bremont, Beatrice; Shen, Shuren; Poncet, Annie; Andrieux, Jean; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 12 p. 2050 - 2060
反应条件
1: diethyl ether
2: acetic acid anhydride
View Scheme
参考文献
Guillaumin
Bulletin de la Societe Chimique de France, 1910 , vol. <4> 7, p. 334
反应条件
sodium azide; CuSO4‵5H2O; [bis(acetoxy)iodo]benzene in acetonitrile
T=-40 - 25°C; Inert atmosphere;
参考文献
Zhou, Wang; Zhang, Liangren; Jiao, Ning
Angewandte Chemie, International Edition, 2009 , vol. 48, # 38 p. 7094 - 7097
Angewandte Chemie, 2009 , vol. 121, # 38 p. 7228 - 7231
