4,4-二乙氧基-3-氧代-戊酸乙酯合成路线 （共 13 条）
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: NBS / H2O; acetone
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: NBS / H2O; acetone
5: 90 percent / NaH / tetrahydrofuran / 0.33 h / 25 °C
6: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C
7: 53 percent / 4 h / 110 °C
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: NBS / H2O; acetone
5: 90 percent / NaH / tetrahydrofuran / 0.33 h / 25 °C
6: MCPBA / CH2Cl2 / 1) -78 deg C, 2) 25 deg C
7: 53 percent / 4 h / 110 °C
8: 56 percent / Cu(OAc)2*H2O / 1 h / 70 °C
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: 78 percent / peracetic acid / tetrahydrofuran; H2O / 4.5 h / 45 °C
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: 78 percent / peracetic acid / tetrahydrofuran; H2O / 4.5 h / 45 °C
5: 95 percent / pyridine / 0.08 h / 55 °C
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: 86 percent / 2 h / Heating
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: 86 percent / 2 h / Heating
5: 901 mg / pyridine / 1.5 h / 0 °C
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: 86 percent / 2 h / Heating
5: 901 mg / pyridine / 1.5 h / 0 °C
6: 1.) 88percent formic acid, 2.) Ac2O / 1) 100 deg C, 30 min, 2) 100 deg C, 5 min
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
反应条件
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: NBS / H2O; acetone
5: 93 percent / acetic acid / 0.33 h / 100 °C
View Scheme
参考文献
Keana; Boyle; Erion; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 21 p. 3621 - 3626
