N-(2-溴乙基)甲烷磺酰胺合成路线 （共 4 条）
反应条件
n-butyllithium; 1,10-phenanthroline; diisopropylamine in tetrahydrofuran; hexane T=-50 - 0°C; 4 h;
参考文献
Lee, Jaemoon; Zhong, Yong-Li; Reamer, Robert A.; Askin, David
Organic Letters, 2003 , vol. 5, # 22 p. 4175 - 4177
反应条件
triethylamine in dichloromethane
参考文献
SmithKline Beecham p.l.c.
Patent: US5852014 A1, 1998 ;
US 5852014 A
反应条件
1: 2-bromo-ethylamine-hydrobromide With triethylamine in dichloromethane
0.5 h;
2: methanesulfonyl chloride in dichloromethane
T=0 - 20°C; 3 h;
3: With water in dichloromethane
参考文献
ASTRAZENECA AB
Patent: WO2005/123747 A1, 2005 ;
Location in patent: Page/Page column 65 ;
WO 2005/123747 A1
反应条件
triethylamine in dichloromethane
T=0°C;
参考文献
EURO-CELTIQUE, S.A
Patent: WO2003/101953 A2, 2003 ;
Location in patent: Page 53-54 ;
WO 03/101953 A2
