2-(1H-吡唑-1-基)乙醇合成路线 (共 4 条)
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in 1,4-dioxane T=75°C; 2 h;
参考文献
Asratyan; Attaryan; Pogosyan; Eliazyan; Darbinyan; Matsoyan
Journal of applied chemistry of the USSR, 1986 , vol. 59, # 6 1 p. 1202 - 1206
反应条件
N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide in 1,4-dioxane T=80°C;
参考文献
Russian Journal of General Chemistry, , vol. 79, # 11 p. 2417 - 2419
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=20°C; 2 h;
参考文献
FUJISAWA PHARMACEUTICAL CO. LTD.; WAKUNAGA PHARMACEUTICAL CO. LTD.
Patent: WO2004/101571 A1, 2004 ;
Location in patent: Page 30 ;
反应条件
1: 38 percent / pyridine / 2 h
2: 47 percent / potassium carbonate / dimethylformamide / 3 h / Ambient temperature
View Scheme
参考文献
Machin, Peter J.; Hurst, David N.; Bradshaw, Rachel M.; Blaber, Leslie C.; Burden, David T.; Melarange, Rosemary A.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 4 p. 503 - 509