4,5-亚甲基-2-硝基肉桂酸合成路线 （共 8 条）
反应条件
nitric acid β-<6-nitro-3.4-methylenedioxy-phenyl>-acrylic acid;
参考文献
Journal of the Chemical Society, , vol. 59, p. 152
反应条件
1: sodium acetate 2: nitric acid View Scheme
参考文献
Journal of the Chemical Society, , vol. 59, p. 152
反应条件
sodium acetate β-<6-nitro-3.4-methylenedioxy-phenyl>-acrylic acid;
参考文献
Journal of the Chemical Society, , vol. 59, p. 152
反应条件
1: SnCl2, conc. HCl 2: 1.) aq. HCl, formic acid, NaNO2, 2.) NaN3; / 1.) acetic acid, 70 min, -5 deg C, 2.) 20 min; 3: 67 percent / various solvent(s) / 0.07 h / Heating View Scheme
参考文献
Lutz; McNamara; Olinger; et al.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 4 p. 1183 - 1188
反应条件
hydrogenchloride
ethyl ester;
参考文献
Perkin,F. M.
Journal of the Chemical Society, 1891 , vol. 59, p. 152
反应条件
1: acetic acid; bromine
2: aq. NaOH solution
3: FeSO4; aqueous NH3 / Erwaermen des in wss. HCl diazotierten Reaktionsprodukts
View Scheme
参考文献
Schofield; Simpson
Journal of the Chemical Society, 1945 , p. 512,519
反应条件
ammonia; iron(II) sulfate
6-amino-3.4-methylenedioxy-cinnamic acid;
参考文献
Hari, Anitha; Miller, Benjamin L.
Organic Letters, 2000 , vol. 2, # 23 p. 3667 - 3670
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol; N,N-dimethyl-formamide
T=22°C; P=760 Torr; Yield given;
参考文献
Hansen, John Bondo; Fink-Jensen, Anders; Christensen, Birgitte V.; Gronvald, Frederick C.; Jeppesen, Lone; Mogensen, John P.; Nielsen, Erik B.; Scheideler, Mark A.; White, Francis J.; Zhang, Xu-Feng
European Journal of Medicinal Chemistry, 1998 , vol. 33, # 11 p. 839 - 858
