3,6-二羟基-2-(3-甲基-3-丁烯-1-炔-1-基)苯甲醛合成路线 （共 18 条）
反应条件
1: 79 percent / cuprous iodide; bis(triphenylphosphine) palladium dichloride; triethylamine / dimethylformamide / 3 h / 60 °C
2: 60 percent / TFA / CH2Cl2 / 6 h / 0 °C
View Scheme
参考文献
Goddard, Mary-Lorene; Tabacchi, Raffaele
Tetrahedron Letters, 2006 , vol. 47, # 6 p. 909 - 911
反应条件
1: 97 percent / Br2 / CHCl3 / 3 h / 20 °C
2: 80 percent / i-Pr2EtN / CH2Cl2 / 1 h / 20 °C
3: 79 percent / cuprous iodide; bis(triphenylphosphine) palladium dichloride; triethylamine / dimethylformamide / 3 h / 60 °C
4: 60 percent / TFA / CH2Cl2 / 6 h / 0 °C
View Scheme
参考文献
Goddard, Mary-Lorene; Tabacchi, Raffaele
Tetrahedron Letters, 2006 , vol. 47, # 6 p. 909 - 911
反应条件
1: 80 percent / i-Pr2EtN / CH2Cl2 / 1 h / 20 °C
2: 79 percent / cuprous iodide; bis(triphenylphosphine) palladium dichloride; triethylamine / dimethylformamide / 3 h / 60 °C
3: 60 percent / TFA / CH2Cl2 / 6 h / 0 °C
View Scheme
参考文献
Goddard, Mary-Lorene; Tabacchi, Raffaele
Tetrahedron Letters, 2006 , vol. 47, # 6 p. 909 - 911
反应条件
hydrogenchloride; acetic acid
参考文献
Orr,A.F.
Journal of the Chemical Society, Chemical Communications, 1979 , p. 40 - 41
反应条件
1: (i) nBuLi, (ii) MeSO2Cl, Py
2: (i) aq. AcOH, (ii) MnO2
3: aq. HCl, AcOH
View Scheme
参考文献
Orr,A.F.
Journal of the Chemical Society, Chemical Communications, 1979 , p. 40 - 41
反应条件
1: (i) NaNH2, liq. NH3, (ii) /BRN= 505999/, imidazole, DMF
2: (i) nBuLi, (ii) MeSO2Cl, Py
3: (i) aq. AcOH, (ii) MnO2
4: aq. HCl, AcOH
View Scheme
参考文献
Orr,A.F.
Journal of the Chemical Society, Chemical Communications, 1979 , p. 40 - 41
反应条件
1: (i) aq. AcOH, (ii) MnO2
2: aq. HCl, AcOH
View Scheme
参考文献
Orr,A.F.
Journal of the Chemical Society, Chemical Communications, 1979 , p. 40 - 41
参考文献
Ronald,R.C.; Lansinger,J.M.
Journal of the Chemical Society, Chemical Communications, 1979 , p. 124 - 125
