Jahromi, Amin Haghighat; Fu, Yuan; Miller, Kali A.; Nguyen, Lien; Luu, Long M.; Baranger, Anne M.; Zimmerman, Steven C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9471 - 9481
1: thionyl chloride; N,N-dimethyl-formamide / 2 h / 70 °C
2: triethylamine / dichloromethane / 15 h / 0 - 20 °C / pH 11 / |Inert atmosphere
View Scheme
参考文献
Jahromi, Amin Haghighat; Fu, Yuan; Miller, Kali A.; Nguyen, Lien; Luu, Long M.; Baranger, Anne M.; Zimmerman, Steven C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9471 - 9481
1: PPA / 120 °C
2: thionyl chloride; N,N-dimethyl-formamide / 2 h / 70 °C
3: triethylamine / dichloromethane / 15 h / 0 - 20 °C / pH 11 / |Inert atmosphere
View Scheme
参考文献
Jahromi, Amin Haghighat; Fu, Yuan; Miller, Kali A.; Nguyen, Lien; Luu, Long M.; Baranger, Anne M.; Zimmerman, Steven C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9471 - 9481
1: potassium carbonate; copper; copper(I) oxide / N,N-dimethyl-formamide / 24 h / |Reflux
2: PPA / 120 °C
3: thionyl chloride; N,N-dimethyl-formamide / 2 h / 70 °C
4: triethylamine / dichloromethane / 15 h / 0 - 20 °C / pH 11 / |Inert atmosphere
View Scheme
参考文献
Jahromi, Amin Haghighat; Fu, Yuan; Miller, Kali A.; Nguyen, Lien; Luu, Long M.; Baranger, Anne M.; Zimmerman, Steven C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9471 - 9481
1: potassium carbonate; copper; copper(I) oxide / N,N-dimethyl-formamide / 24 h / |Reflux
2: PPA / 120 °C
3: thionyl chloride; N,N-dimethyl-formamide / 2 h / 70 °C
4: triethylamine / dichloromethane / 15 h / 0 - 20 °C / pH 11 / |Inert atmosphere
View Scheme
参考文献
Jahromi, Amin Haghighat; Fu, Yuan; Miller, Kali A.; Nguyen, Lien; Luu, Long M.; Baranger, Anne M.; Zimmerman, Steven C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9471 - 9481
