5-[1-(4-氯-苯基)-甲-(Z)-亚基]-2-硫代-噻唑烷-4-酮合成路线 （共 9 条）
反应条件
1: 80 percent / NaOH / acetone; H2O / 3 h / Ambient temperature 2: 87 percent / ethanol / Heating View Scheme
参考文献
Omar, M.T.; Sherif, F.A.
Journal fuer Praktische Chemie (Leipzig), 1980 , vol. 322, # 5 p. 835 - 842
反应条件
sodium acetate; acetic anhydride in acetic acid
Heating;
参考文献
Korohoda, Maria Jolanta
Polish Journal of Chemistry, 1981 , vol. 55, # 2 p. 359 - 369
反应条件
T=110°C; Knoevenagel condensation; 0.166667 h; Neat (no solvent);
参考文献
Shah, Sakshi; Singh, Baldev
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 17 p. 5388 - 5391
反应条件
ammonium hydroxide; ammonium chloride in methanol
1 h; Heating;
参考文献
Gorizdra,T.E.; Baranov,S.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 52 - 56
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, p. 67 - 72
反应条件
sodium methylate in methanol
参考文献
Gorizdra,T.E.; Baranov,S.N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 52 - 56
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, p. 67 - 72
反应条件
aluminium trichloride
参考文献
Behringer et al.
Chemische Berichte, 1958 , vol. 91, p. 2773,2783
反应条件
aq. Cl2CH2CO2H
4 h; Heating;
参考文献
Korohoda, Maria Jolanta
Polish Journal of Chemistry, 1981 , vol. 55, # 2 p. 359 - 369
反应条件
sodium hydroxide in tetrahydrofuran; acetone
Ambient temperature;
参考文献
Foye; Tovivich
Journal of Pharmaceutical Sciences, 1977 , vol. 66, # 11 p. 1607 - 1611
反应条件
1: With sodium hydroxide
0.5 h; Reflux;
2: With hydrogenchloride in water
参考文献
Casas, Jose S.; Castano, M. Victoria; Couce, Maria D.; Sanchez, Agustin; Sordo, Jose; Torres, M. Dolores; Vazquez Lopez, Ezequiel M.
European Journal of Inorganic Chemistry, 2013 , # 29 p. 5110 - 5120
