4-氨基-2-甲基苯硼酸频那醇酯合成路线 （共 5 条）
反应条件
ammonium chloride; zinc in tetrahydrofuran; ethanol T=20°C; 2 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; AUSTIN, Joel, Francis; SHARMA, Lisa, S.; BALOG, James, Aaron; HUANG, Audris; VELAPARTHI, Upender; DARNE, Chetan, Padmakar; SAULNIER, Mark, George
Patent: WO2012/15723 A1, 2012 ;
Location in patent: Page/Page column 87; 88 ;
WO 2012/015723 A1
反应条件
triethylamine; PdCl2(PPh3)2 in 1,4-dioxane
参考文献
3-Dimensional Pharmaceuticals, Inc.
Patent: US2004/9995 A1, 2004 ;
反应条件
1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 80 °C 2: zinc; ammonium chloride / ethanol; tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
WO2012/15723 A1, ;
WO 2012/015723 A1
反应条件
1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 80 °C 2: zinc; ammonium chloride / ethanol; tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
WO2012/15723 A1, ;
WO 2012/015723 A1
反应条件
1: 2-(4-biphenylyl)-5-phenyl-oxazole; tert.-butylnitrite / acetonitrile / 4 h / 20 °C 2: 5 palladium on charcoal; hydrogen / methanol / 4 h / 20 °C / 760.05 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 79, # 5 p. 1979 - 1988
