1,1,3,3-四甲基脲合成路线 （共 85 条）
反应条件
P=0.008 - 0.8 Torr; radio-frequency discharge; Yield given. Yields of byproduct given;
参考文献
Yajima, Tatsuhiko; Tsuchiya, Atsuhiko; Tezuka, Meguru
Tetrahedron Letters, 1987 , vol. 28, # 36 p. 4177 - 4178
反应条件
1: phosgene / toluene / 0.25 h 2: aq. ammonium hexafluorophosphate / CH2Cl2 3: 100 percent / N(C2H5)3 / CH2Cl2 View Scheme
参考文献
Knorr, Reinhard; Trzeciak, Arnold; Bannwarth, Willi; Gillessen, Dieter
Tetrahedron Letters, 1989 , vol. 30, # 15 p. 1927 - 1930
参考文献
The United States of America as represented by the Secretary of Agriculture
Patent: US4477389 A1, 1984 ;
反应条件
1: dimethyl amine; N,N,N',N'-tetramethyl-urea; trichloromethyl chloroformate in tetrahydrofuran T=20°C; Substitution; condensation; 2: boric acid trimethyl ester With sodium hydride in tetrahydrofuran T=20°C; Substitution; 24 h; Title compound not separated from byproducts;
参考文献
Kantlehner, Willi; Stieglitz, Ruediger; Hauber, Michael; Haug, Erwin; Regele, Claudia
Journal fuer Praktische Chemie - Practical Applications and Applied Chemistry (Germany), 2000 , vol. 342, # 3 p. 256 - 268
参考文献
Grushin, Vladimir; Herron, Norman; Halliday, Gary A.
Patent: US2003/130528 A1, 2003 ;
反应条件
2C6H15N*ClH*Cl2HOPS in chloroform 10 h; Reflux;
参考文献
Bezgubenko; Pipko; Sinitsa
Russian Journal of General Chemistry, 2008 , vol. 78, # 7 p. 1341 - 1344
反应条件
1: dimethyl amine; N,N,N',N'-tetramethyl-urea; trichloromethyl chloroformate in tetrahydrofuran T=20°C; Substitution; condensation; 2: boric acid trimethyl ester With sodium hydride in tetrahydrofuran T=20°C; Substitution; 24 h; Title compound not separated from byproducts;
参考文献
Kantlehner, Willi; Stieglitz, Ruediger; Hauber, Michael; Haug, Erwin; Regele, Claudia
Journal fuer Praktische Chemie - Practical Applications and Applied Chemistry (Germany), 2000 , vol. 342, # 3 p. 256 - 268
反应条件
1: oxalyl chloride 2: KBF4, HCl View Scheme
参考文献
Tetrahedron Letters, , vol. 30, # 15 p. 1927 - 1930
反应条件
[RuH(CO)(BPy-tPNN*)]; hydrogen in tetrahydrofuran T=110°C; P=10336.7 Torr; 72 h; chemoselective reaction;
参考文献
Balaraman, Ekambaram; Ben-David, Yehoshoa; Milstein, David
Angewandte Chemie - International Edition, 2011 , vol. 50, # 49 p. 11702 - 11705
反应条件
sodium hydroxide in water T=25°C; hydrolytic decomposition; Rate constant;
参考文献
Kankaanperae, Alpo; Scharlin, Pirketta; Kuusisto, Ilona; Kallio, Riitta; Bernoulli, Emma
Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 2 p. 169 - 174
