1,1,3,3-四甲基脲合成路线 （共 85 条）
反应条件
1.1: phosgene / acetonitrile / -5 - 20 °C
2.1: triethylamine / 20 °C / Reflux
2.2: 0.5 h / 20 °C
View Scheme
参考文献
Kantlehner, Willi; Jochenmezger; Kress, Ralf; Hartmann, Horst; Moschny, Thorsten; Tiritiris, Ioannis; Iliev, Boyan; Scherr, Oliver; Ziegler, Georg; Souley, Bahari; Frey, Wolfgang; Ivanov, Ivo C.; Bogdanov, Milen G.; Jaeger, Ulrich; Dospil, Guenther; Viefhaus, Tillmann
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2010 , vol. 65, # 7 p. 873 - 906
反应条件
1: N,N,N',N'-tetramethyl-urea With oxalyl dichloride in dichloromethane
T=60°C; 18 h;
2: n-Octylamine in acetonitrile
T=60°C; 4 h;
3: With potassium carbonate; sodium hydroxide in diethyl ether; water
T=0°C;
参考文献
Arthur, Troy; Harjani, Jitendra R.; Phan, Lam; Jessop, Philip G.; Hodson, Peter V.
Green Chemistry, 2012 , vol. 14, # 2 p. 357 - 362
反应条件
1.1: phosgene / acetonitrile / -5 - 20 °C
2.1: triethylamine / 20 °C / Reflux
2.2: 0.5 h / 20 °C
View Scheme
参考文献
Kantlehner, Willi; Jochenmezger; Kress, Ralf; Hartmann, Horst; Moschny, Thorsten; Tiritiris, Ioannis; Iliev, Boyan; Scherr, Oliver; Ziegler, Georg; Souley, Bahari; Frey, Wolfgang; Ivanov, Ivo C.; Bogdanov, Milen G.; Jaeger, Ulrich; Dospil, Guenther; Viefhaus, Tillmann
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2010 , vol. 65, # 7 p. 873 - 906
反应条件
trichlorophosphate
1.) benzene, RT, 2.) benzene, 70 deg C, 7 h; Yield given. Multistep reaction;
参考文献
Nogaj, Boleslaw; Pruszynszki, Przemyslav
Magnetic Resonance in Chemistry, 1987 , vol. 25, p. 301 - 304
反应条件
1: COCl2 / toluene
2: acetonitrile
View Scheme
参考文献
Eilingsfeld,H. et al.
Chemische Berichte, 1964 , vol. 97, p. 1232 - 1245
反应条件
1: 95 percent / phosgene / 26 h / 0 - 20 °C
2: 85 percent / Et3N / acetonitrile / 3 h / Heating
View Scheme
参考文献
Raab, Volker; Kipke, Jennifer; Gschwind, Ruth M.; Sundermeyer, Joerg
Chemistry - A European Journal, 2002 , vol. 8, # 7 p. 1682 - 1693
反应条件
1: N,N,N',N'-tetramethyl-urea With trichlorophosphate in toluene
T=20°C;
2: cyclohexylamine in toluene
Heating;
参考文献
Garcia-Egido, Eduardo; Fernandez, Isabelle; Munoz, Luis
Synthetic Communications, 2006 , vol. 36, # 20 p. 3029 - 3042
反应条件
bis(trimethylsilyl)selenide; boron trifluoride diethyl etherate in benzene
T=150°C; 24 h;
参考文献
Takikawa, Yuji; Watanabe, Hiroyuki; Sasaki, Ryuji; Shimada, Kazuaki
Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 3 p. 876 - 878
反应条件
in acetonitrile
Irradiation;
参考文献
Tsujimoto,Y. et al.
Bulletin of the Chemical Society of Japan, 1976 , vol. 49, p. 3705 - 3706
反应条件
in acetonitrile
Irradiation;
参考文献
Tsujimoto,Y. et al.
Bulletin of the Chemical Society of Japan, 1976 , vol. 49, p. 3705 - 3706
