6-氯-2,4-甲氧基嘧啶合成路线 （共 13 条）
反应条件
1: ethanolic sodium ethylate; H2S
2: aqueous NaOH
View Scheme
参考文献
Greenbaum
Journal of the American Chemical Society, 1954 , vol. 76, p. 6052
反应条件
bromine; sodium hydrogencarbonate in methanol; water
T=20°C; 2 h; Product distribution / selectivity;
参考文献
Guo, Hongyan; Kim, Choung U.; Kim, Hae Soo; Lee, Chong-Kyo; Lee, Ill Young; Mitchell, Michael L.; Son, Jong Chan; Xu, Lianhong
Patent: US2008/70920 A1, 2008 ;
Location in patent: Page/Page column 99-100; 109 ;
反应条件
sulfuric acid in water
4 h; Heating;
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
