N-(3-硝基苯基)甲烷磺酰胺合成路线 （共 7 条）
反应条件
iron; ammonium chloride in methanol; water T=70°C; P=760.051 Torr; Inert atmosphere;
参考文献
F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; BILOTTA, Joseph Anthony; CHEN, Zhi; CHIN, Elbert; DING, Qingjie; ERICKSON, Shawn David; GABRIEL, Stephen Deems; KLUMPP, Klaus; MA, Han; MERTZ, Eric; PLANCHER, Jean-Marc; WEIKERT, Robert James
Patent: WO2014/6066 A1, 2014 ;
Location in patent: Paragraph 0235 ;
参考文献
Diab, Sarah; Teo, Theodosia; Kumarasiri, Malika; Li, Peng; Yu, Mingfeng; Lam, Frankie; Basnet, Sunita K. C.; Sykes, Matthew J.; Albrecht, Hugo; Milne, Robert; Wang, Shudong
ChemMedChem, 2014 , vol. 9, # 5 p. 962 - 972
反应条件
1: With triethylamine in dichloromethane
T=20°C;
2: With sodium hydroxide in methanol; water
T=20°C;
参考文献
Greenfield, Alexander; Grosanu, Cristina
Tetrahedron Letters, 2008 , vol. 49, # 44 p. 6300 - 6303
反应条件
copper(I) oxide; caesium carbonate in water
T=130°C; 24 h; Sealed tube;
参考文献
Tan, Bryan Yong-Hao; Teo, Yong-Chua; Seow, Ai-Hua
European Journal of Organic Chemistry, 2014 , vol. 2014, # 7 p. 1541 - 1546
参考文献
F. HOFFMANN-LA ROCHE AG
Patent: EP887346 A2, 1998 ;
EP 0887346 A2
Title/Abstract Full Text Show Details
Syntex (U.S.A) Inc.
Patent: US5952362 A1, 1999 ;
US 5952362 A
反应条件
1: K2CO3 / dimethylformamide
2: 64 percent / t-BuOK / dimethylformamide / 0.5 h / 10 - 15 °C
View Scheme
参考文献
Wojciechowski, K.
Polish Journal of Chemistry, 1992 , vol. 66, # 7 p. 1121 - 1124
反应条件
1: iron; acetic acid / methanol / 50 °C / |Inert atmosphere
2: chloro-trimethyl-silane / acetonitrile / 20 °C / |Reflux
View Scheme
参考文献
Diab, Sarah; Teo, Theodosia; Kumarasiri, Malika; Li, Peng; Yu, Mingfeng; Lam, Frankie; Basnet, Sunita K. C.; Sykes, Matthew J.; Albrecht, Hugo; Milne, Robert; Wang, Shudong
ChemMedChem, 2014 , vol. 9, # 5 p. 962 - 972
