1-Boc-3-苯基哌啶-4-酮合成路线 （共 7 条）
反应条件
4-(N,N-dimethlyamino)pyridine in methanol T=23°C; 0.5 h;
参考文献
Rosiak, Anna; Hoenke, Christoph; Christoffers, Jens
European Journal of Organic Chemistry, 2007 , # 26 p. 4376 - 4382
反应条件
triethylamine in acetonitrile 14 h;
参考文献
Shirai, Junya; Yoshikawa, Takeshi; Yamashita, Masayuki; Yamamoto, Yasuharu; Kawamoto, Makiko; Tarui, Naoki; Kamo, Izumi; Hashimoto, Tadatoshi; Ikeura, Yoshinori
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 21 p. 6430 - 6446
反应条件
caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; bis(dibenzylideneacetone)-palladium(0) in toluene T=80°C;
参考文献
Journal of the American Chemical Society, , vol. 136, # 14 p. 5225 - 5228
反应条件
1: hydrogenchloride / ethyl acetate 2: palladium 10 on activated carbon; hydrogen / methanol / 2 h / 55 °C / 3800.26 Torr 3: triethylamine / acetonitrile / 14 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 21 p. 6430 - 6446
反应条件
1: hydrogenchloride; water; acetic acid / 5 h / 125 °C 2: hydrogenchloride / ethyl acetate 3: palladium 10 on activated carbon; hydrogen / methanol / 2 h / 55 °C / 3800.26 Torr 4: triethylamine / acetonitrile / 14 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 21 p. 6430 - 6446
反应条件
1: palladium 10 on activated carbon; hydrogen / methanol / 2 h / 55 °C / 3800.26 Torr 2: triethylamine / acetonitrile / 14 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 21 p. 6430 - 6446
反应条件
1: With ammonium chloride in methanol
1 h; 4A molecular sieve;
2: With sodium cyanoborohydride in methanol
1 h;
参考文献
Shirai, Junya; Yoshikawa, Takeshi; Yamashita, Masayuki; Yamamoto, Yasuharu; Kawamoto, Makiko; Tarui, Naoki; Kamo, Izumi; Hashimoto, Tadatoshi; Ikeura, Yoshinori
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 21 p. 6430 - 6446
