1,4-二溴-2,5-二碘苯合成路线 （共 27 条）
反应条件
water in tetrahydrofuran Ambient temperatureexamination with further bromo-iodo-benzenes, and Grignard reagents; addition of lithium 2,2,6,6-tetramethylpiperidide or potassium t-butoxide; other reagent: iodine; Product distributionMechanism;
参考文献
Tetrahedron Letters, , vol. 26, # 1 p. 29 - 32
反应条件
in tetrahydrofuran 3.5 h; Ambient temperature; Yield given;
参考文献
Hart, Harold; Harada, Katsumasa; Du, Chi-Jen Frank
Journal of Organic Chemistry, 1985 , vol. 50, # 17 p. 3104 - 3110
反应条件
in tetrahydrofuran 2 h; Ambient temperature; Yield given;
参考文献
Hart, Harold; Harada, Katsumasa; Du, Chi-Jen Frank
Journal of Organic Chemistry, 1985 , vol. 50, # 17 p. 3104 - 3110
反应条件
in tetrahydrofuran 2.5 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Hart, Harold; Harada, Katsumasa; Du, Chi-Jen Frank
Journal of Organic Chemistry, 1985 , vol. 50, # 17 p. 3104 - 3110
反应条件
1: 89 percent / diethylamine; PdCl2(PPh3)2; CuI / 8 h / 25 °C 2: 73 percent / Pd(PPh3)4; K2CO3 / tetrahydrofuran / 24 h / 65 °C 3: 93 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h / 0 °C 4: 83 percent / TpRuPPh3(CH3CN)PF6 / 1,2-dichloro-ethane / 24 h / 80 °C View Scheme
参考文献
Shen, Hung-Chin; Tang, Jhih-Meng; Chang, Hsu-Kai; Yang, Chia-Wei; Liu, Rai-Shung
Journal of Organic Chemistry, 2005 , vol. 70, # 24 p. 10113 - 10116
反应条件
potassium fluoride; palladium diacetate Suzuki coupling reaction; 0.116667 h; microwave irradiation;
参考文献
Basu, Basudeb; Das, Pralay; Bhuiyan, Md. Mosharef H.; Jha, Satadru
Tetrahedron Letters, 2003 , vol. 44, # 19 p. 3817 - 3820
反应条件
in tetrahydrofuran 3.5 h; Ambient temperature; Yield given;
参考文献
Hart, Harold; Harada, Katsumasa; Du, Chi-Jen Frank
Journal of Organic Chemistry, 1985 , vol. 50, # 17 p. 3104 - 3110
反应条件
1.1: 97 percent / PdCl2(PPh3)2; CuI; diisopropylamine / benzene / 1 h / 20 °C 2.1: t-BuLi / diethyl ether; pentane / -78 - 20 °C 2.2: 70 percent / S / diethyl ether; pentane / 0.25 h / 20 °C 3.1: 96 percent / Bu4NF / tetrahydrofuran / 3 h / 20 °C View Scheme
参考文献
Takimiya, Kazuo; Konda, Yasushi; Ebata, Hideaki; Niihara, Naoto; Otsubo, Tetsuo
Journal of Organic Chemistry, 2005 , vol. 70, # 25 p. 10569 - 10571
反应条件
in tetrahydrofuran
4 h; Ambient temperature;
参考文献
Du, Chi-Jen Frank; Hart, Harold
Journal of Organic Chemistry, 1987 , vol. 52, # 19 p. 4311 - 4314
反应条件
potassium carbonate; copper(l) iodide in tetrahydrofuran
T=100°C; 24 h;
参考文献
Lu, Biao; Wang, Bao; Zhang, Yihua; Ma, Dawei
Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5337 - 5341
