(1S,2R)--2-羟基环己腈合成路线 （共 33 条）
反应条件
lithium perchlorate in acetonitrile
T=70°C; 24 h;
参考文献
Chini, Marco; Crotti, Paolo; Favero, Lucilla; Macchia, Franco
Tetrahedron Letters, 1991 , vol. 32, # 36 p. 4775 - 4778
反应条件
ytterbium cyanide in tetrahydrofuran
T=25°C; 1 h;
参考文献
Matsubara, Seijiro; Onishi, Hitoshi; Utimoto, Kiitiro
Tetrahedron Letters, 1990 , vol. 31, # 43 p. 6209 - 6212
反应条件
sodium cyanide; zirconium tetrakis(dodecyl sulfate) in water
T=20°C; 6 h;
参考文献
Jafarpour, Maasoumeh; Rezaeifard, Abdolreza; Aliabadi, Marzieh
Helvetica Chimica Acta, 2010 , vol. 93, # 3 p. 405 - 413
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
T=82°C; 6 h;
参考文献
Konno, Hiroyuki; Toshiro, Emi; Hinoda, Naoyuki
Synthesis, 2003 , # 14 p. 2161 - 2164
反应条件
tri-i-propoxy lanthanium in tetrahydrofuran
T=50°C; 4 h;
参考文献
Ohno, Hiroshi; Mori, Atsunori; Inoue, Shohei
Chemistry Letters, 1993 , # 6 p. 975 - 978
反应条件
cerium(IV) triflate; sodium lauryl sulfate
T=20°C; 5 h;
参考文献
Iranpoor, Nasser; Firouzabadi, Habib; Shekarize, Marzieh
Organic and Biomolecular Chemistry, 2003 , vol. 1, # 4 p. 724 - 727
反应条件
1: [-OC(C6H5)2CH2CH2C(C6H5)2O-]Zr(O-tBu)2; Ph3PO; bis(trimethylsilyl)peroxide / 1,2-dichloro-ethane / 12 h / 20 °C
2: KF / methanol
View Scheme
参考文献
Yamasaki; Kanai; Shibasaki
Journal of the American Chemical Society, 2001 , vol. 123, # 6 p. 1256 - 1257
反应条件
1,4,7,10-tetraoxa-cyclododecane in water; acetonitrile
T=45°C; 40 h;
参考文献
Yang; Shah; Rao; Freeman; Sosnovsky; Gorenstein
Tetrahedron, 1988 , vol. 44, # 20 p. 6305 - 6314
反应条件
in tetrahydrofuran
0.5 h; Heating;
参考文献
Ciaccio, James A.; Smrtka, Michael; Maio, William A.; Rucando, David
Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7201 - 7204
反应条件
in tetrahydrofuran
4 h; Heatingother epoxides;
参考文献
Ciaccio; Stanescu; Bontemps
Tetrahedron Letters, 1992 , vol. 33, # 11 p. 1431 - 1434
