2-(4-甲氧基-3-硝基苯基)乙酸合成路线 （共 16 条）
参考文献
Bersch
Archiv der Pharmazie (Weinheim, Germany), 1939 , vol. 277, p. 271,281
反应条件
1: hydrogen chloride 2: palladium; ethyl acetate / Hydrogenation View Scheme
参考文献
Bersch
Archiv der Pharmazie (Weinheim, Germany), 1939 , vol. 277, p. 271,281
反应条件
1.1: 85 percent / hydrogen / palladium catalyst / methanol / 25 °C / 2327.17 Torr 2.1: sodium nitrite; sulfuric acid / acetic acid / 0 °C 2.2: 86 percent / sodium azide / acetic acid / 0.5 h / 20 °C 3.1: 80 percent / dicyclohexylcarbodiimide; Et3N / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Rodrigues, J. Augusto R.; Abramovitch, Rudolph A.; De Sousa, Joana D. F.; Leiva, Genaro C.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 2920 - 2928
反应条件
1: palladium; methanol / Hydrogenation 2: aqueous sulfuric acid; sodium nitrite / Eintragen der Reaktionsloesung in heisse wss. Schwefelsaeure View Scheme
参考文献
Burger; Avakian
Journal of Organic Chemistry, 1940 , vol. 5, p. 606,608
反应条件
potassium carbonate; acetic acid in hydrogenchloride; methanol; acetone
参考文献
Kumar, Virendra; Guo, Deqi; Marella, Michael Anthony; Maycock, Alan L.
Patent: US2003/144272 A1, 2003 ;
反应条件
1: With sodium hydroxide
T=90°C;
2: With dihydrogen peroxide
参考文献
Rodrigues, J. Augusto R.; Abramovitch, Rudolph A.; De Sousa, Joana D. F.; Leiva, Genaro C.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 2920 - 2928
反应条件
1.1: 78 percent / acetyl nitrate / acetonitrile / 0 - 20 °C
2.1: 100 percent / sodium acetate / 0.08 h / microwave irradiation
3.1: NaOH / 90 °C
3.2: 80 percent / H2O2
View Scheme
参考文献
Rodrigues, J. Augusto R.; Abramovitch, Rudolph A.; De Sousa, Joana D. F.; Leiva, Genaro C.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 2920 - 2928
参考文献
Bersch
Archiv der Pharmazie (Weinheim, Germany), 1939 , vol. 277, p. 271,281
反应条件
1: aqueous ethanol
2: aqueous hydrochloric acid
View Scheme
参考文献
Bersch
Archiv der Pharmazie (Weinheim, Germany), 1939 , vol. 277, p. 271,281
反应条件
nitric acid; acetic acid
参考文献
Burger; Avakian
Journal of Organic Chemistry, 1940 , vol. 5, p. 606,608
