2-(4-氯苯基)-1-苯乙酮合成路线 （共 67 条）
反应条件
palladium diacetate; 1,4-di(diphenylphosphino)-butane; zinc in 1,4-dioxane T=100°C; Negishi coupling reaction; P=7500.75 Torr; 16 h; Inert atmosphereAutoclave;
参考文献
Wu, Xiao-Feng; Schranck, Johannes; Neumann, Helfried; Beller, Matthias
Chemistry - An Asian Journal, 2012 , vol. 7, # 1 p. 40 - 44
反应条件
sodium hydride in tetrahydrofuran 14 h; Heating;
参考文献
Ishikawa, Yoshiharu; Kurebayashi, Yasuo; Suzuki, Kunio; Terao, Yoshiyasu; Sekiya, Minoru
Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 9 p. 2496 - 2502
反应条件
1: With 3,3-dimethyl-butan-2-one T=20°C; Oppenauer Oxidation; 3 h; Cooling with ice; 2: With trifluoroacetic acid T=20°C; 48 h;
参考文献
Fu, Ying; Yang, Yanshou; Huegel, Helmut M.; Du, Zhengyin; Wang, Kehu; Huang, Danfeng; Hu, Yulai
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 27 p. 4429 - 4432
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Prakash, Om; Kumar, Rajesh; Sharma, Deepak; Pannu, Kamaljeet; Kamal, Raj
Synlett, 2007 , # 14 p. 2189 - 2192
反应条件
pyridine T=0°C; 3.5 h;
参考文献
Sakakura, Toshiyasu; Hara, Masayasu; Tanaka, Masato
Journal of the Chemical Society, Chemical Communications, 1985 , # 21 p. 1545 - 1546
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Sakakura, Toshiyasu; Hara, Masayasu; Tanaka, Masato
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 3 p. 283 - 288
反应条件
lithium bromide in diethyl ether T=-5 - 0°C; protected from light;
参考文献
Loeschorn, Carol A.; Nakajima, Masayuki; McCloskey, Patrick J.; Anselme, Jean-Pierre
Journal of Organic Chemistry, 1983 , vol. 48, # 23 p. 4407 - 4410
反应条件
bis-triphenylphosphine-palladium(II) chloride; zinc in ethylene glycol dimethyl ether 0.333333 h; Ambient temperature;
参考文献
Sato, Toshio; Naruse, Kouichi; Enokiya, Masashi; Fujisawa, Tamotsu
Chemistry Letters, 1981 , p. 1135 - 1138
反应条件
diethylzinc in dichloromethane T=20°C; 2 h; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 73, # 9 p. 3516 - 3522
反应条件
sodium hydroxide in ethanol T=60°C; Substitution; 21 h; Product distribution; Further Variations:SolventsReagentsTemperaturesreaction time;
参考文献
Angle, Steven R.; Neitzel, Martin L.
Journal of Organic Chemistry, 2000 , vol. 65, # 20 p. 6458 - 6461
反应条件
1: SOCl2 / 3 h / Heating 2: AlCl3 / 0.75 h / 20 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds, , vol. 42, # 7 p. 901 - 906
