5-氯-1H-吡唑并[4,3-d]嘧啶合成路线 （共 3 条）
反应条件
hydrogenchloride in tetrahydrofuran
T=50°C; Reflux;
参考文献
Heald, Robert; Price, Stephen; Safina, Brian; Savy, Pascal Pierre Alexandre; Seward, Eileen Mary; Sutherlin, Daniel P.; Waszkowycz, Bohdan
Patent: US2012/202785 A1, 2012 ;
Location in patent: Page/Page column 263 ;
反应条件
1: acetic anhydride; potassium acetate; isopentyl nitrite / chloroform / Reflux
2: hydrogenchloride / tetrahydrofuran / 50 °C / Reflux
View Scheme
参考文献
Heald, Robert; Price, Stephen; Safina, Brian; Savy, Pascal Pierre Alexandre; Seward, Eileen Mary; Sutherlin, Daniel P.; Waszkowycz, Bohdan
Patent: US2012/202785 A1, 2012 ;
反应条件
1: acetic acid / 2 h / 20 °C
2: acetic anhydride; potassium acetate; isopentyl nitrite / chloroform / Reflux
3: hydrogenchloride / tetrahydrofuran / 50 °C / Reflux
View Scheme
参考文献
Heald, Robert; Price, Stephen; Safina, Brian; Savy, Pascal Pierre Alexandre; Seward, Eileen Mary; Sutherlin, Daniel P.; Waszkowycz, Bohdan
Patent: US2012/202785 A1, 2012 ;
