1,1-二苯基-2-丁酮合成路线 （共 35 条）
反应条件
sodium amide; benzene
参考文献
Klosa
Chemische Technik (Leipzig, Germany), 1953 , vol. 5, p. 375
反应条件
caesium carbonate; palladium dichloride in N,N-dimethyl-formamide
T=100°C; Phenylation; 4 h;
参考文献
Satoh, Tetsuya; Inoh, Jun-Ichi; Kawamura, Yoshiki; Kawamura, Yuichiro; Miura, Masahiro; Nomura, Masakatsu
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 9 p. 2239 - 2246
反应条件
1: phenyl-magnesium chloride With AlCl3, aluminium chloride in tetrahydrofuran
2: 1-phenyl-2-butanone With dihydro-isoxazole in tetrahydrofuran; dichloromethane
T=0 - 20°C;
参考文献
Miyoshi, Tetsuya; Sato, Shohei; Tanaka, Hiroya; Hasegawa, Chihiro; Ueda, Masafumi; Miyata, Okiko
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4188 - 4191
反应条件
ethanol; nickel
T=80°C; P=60311.6 Torr; Hydrogenation;
参考文献
Schultz; Bicking
Journal of the American Chemical Society, 1955 , vol. 75, p. 1128
参考文献
Brodhag; Hauser
Journal of the American Chemical Society, 1955 , vol. 77, p. 3024,3030
反应条件
hydrogen bromide in tetrahydrofuran
参考文献
Komatsu,M. et al.
Journal of Organic Chemistry, 1974 , vol. 39, p. 3198 - 3205
反应条件
1: 1) KH, 2) n-BuLi / tetrahydrofuran / 1) 30 min, 2) Hexane, 30 min
2: 1.61 g / tetrahydrofuran / 24 h / Ambient temperature; var. alkyl halides, C-1/C-3 ratio of alkylated products
View Scheme
参考文献
Trimitsis, G. B.; Hinkley, J. M.; TenBrink, R.; Faburada, A. L.; Anderson, R.; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 2957 - 2962
反应条件
1: benzene
2: aq. HBr / tetrahydrofuran
View Scheme
参考文献
Komatsu,M. et al.
Journal of Organic Chemistry, 1974 , vol. 39, p. 3198 - 3205
反应条件
tri-tert-butyl phosphine; caesium carbonate; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran; toluene
T=80 - 85°C; Inert atmosphere;
参考文献
Tan, Yichen; Hartwig, John F.
Journal of the American Chemical Society, 2010 , vol. 132, # 11 p. 3676 - 3677
反应条件
trifluoroacetic acid in dichloromethane
Ambient temperature;
参考文献
Dunkelblum,E.
Israel Journal of Chemistry, 1973 , vol. 11, # 4 p. 557 - 566
