反应条件
1: 48 percent / NBS / CCl4 / 1 h / Heating; Irradiation
2: 75 percent / DIEA / dimethylformamide / a) 105 deg C, 1.5 h, b) 85 deg C, 1.5 h
3: 59 percent / DIEA / dimethylformamide / 1.42 h / 75 °C
4: Lawesson's reagent / toluene
5: NaOH / tetrahydrofuran; ethanol
6: NH3 / methanol
View Scheme
参考文献
Varney, Michael D.; Marzoni, Gifford P.; Palmer, Cindy L.; Deal, Judith G.; Webber, Stephanie; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 663 - 676
