1,2,3-三甲氧基苯合成路线 （共 210 条）
反应条件
1: 74 percent / cc. H2SO4 / 4 h / 25 - 30 °C 2: 79 percent / SOCl2 / dimethylformamide / 24 h / Ambient temperature 3: 84 percent / CHCl3 / 4 h / Ambient temperature 4: sat. NaHCO3 / H2O View Scheme
参考文献
Boudet-Dalbin; Durand; Adam; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 2 p. 131 - 137
反应条件
1: 74 percent / cc. H2SO4 / 4 h / 25 - 30 °C 2: 79 percent / SOCl2 / dimethylformamide / 24 h / Ambient temperature 3: 74 percent / Na2SO3 / pH 8-9 4: 58 percent / Na2CO3 / H2O / 4 h / Heating; pH neutr. 5: 85 percent / pyridine, SOCl2 / 3 h / Heating 6: 85 percent / triethylamine / benzene / 24 h / Ambient temperature 7: 83 percent / ethanol / 96 h / Ambient temperature View Scheme
参考文献
Boudet-Dalbin; Durand; Adam; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 2 p. 131 - 137
反应条件
boron trichloride in dichloromethane 3 h; Ambient temperature;
参考文献
Australian Journal of Chemistry, , vol. 38, # 5 p. 777 - 792
反应条件
boron trichloride in dichloromethane 41 h; Ambient temperature;
参考文献
Australian Journal of Chemistry, , vol. 38, # 5 p. 777 - 792
反应条件
potassium in tetrahydrofuran 24 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 1549 - 1550
反应条件
sodium in N,N,N',N',N'',N''-hexamethylphosphoric triamide T=100°C; 2 h;
参考文献
Tetrahedron, , vol. 38, # 24 p. 3687 - 3692
反应条件
toluene Kochen des vom Aether befreiten Reaktionsgemisches;
参考文献
Journal of the American Chemical Society, , vol. 64, p. 2085
反应条件
lithium chloride in N,N-dimethyl-formamide 48 h; Heating; Yield given. Yields of byproduct given;
参考文献
Synthesis, , # 4 p. 287 - 289
反应条件
sodium in benzene T=80°C; 4 h;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 333, # 4 p. 643 - 650
参考文献
Chemische Berichte, , vol. 73, p. 1197,1217
