4-(氯甲基)-5-(2-甲基-2-丙基)-2-糠酰胺合成路线 （共 5 条）
反应条件
ammonium hydroxide in 1,4-dioxane; water
cooling;
参考文献
Pevzner
Russian Journal of General Chemistry, 2003 , vol. 73, # 11 p. 1715 - 1724
反应条件
1: 84 percent / acetic acid / 13 h / 130 °C
2: 5.2 g / KOH / H2O / 6 h / Heating
3: 10.5 g / thionyl chloride / benzene / 6 h / Heating
4: 4 g / aq.NH3 / dioxane; H2O / cooling
View Scheme
参考文献
Pevzner
Russian Journal of General Chemistry, 2003 , vol. 73, # 11 p. 1715 - 1724
反应条件
1: 5.2 g / KOH / H2O / 6 h / Heating
2: 10.5 g / thionyl chloride / benzene / 6 h / Heating
3: 4 g / aq.NH3 / dioxane; H2O / cooling
View Scheme
参考文献
Pevzner
Russian Journal of General Chemistry, 2003 , vol. 73, # 11 p. 1715 - 1724
反应条件
1: 10.5 g / thionyl chloride / benzene / 6 h / Heating
2: 4 g / aq.NH3 / dioxane; H2O / cooling
View Scheme
参考文献
Pevzner
Russian Journal of General Chemistry, 2003 , vol. 73, # 11 p. 1715 - 1724
反应条件
1: 76 percent / ZnCl2; HCl / CCl4 / 2 h / 55 - 60 °C
2: 84 percent / acetic acid / 13 h / 130 °C
3: 5.2 g / KOH / H2O / 6 h / Heating
4: 10.5 g / thionyl chloride / benzene / 6 h / Heating
5: 4 g / aq.NH3 / dioxane; H2O / cooling
View Scheme
参考文献
Pevzner
Russian Journal of General Chemistry, 2003 , vol. 73, # 11 p. 1715 - 1724
