3-(2-甲氧基苯基）丙酸合成路线 （共 42 条）
反应条件
PPA; Polyphosphoric acid (PPA) T=70 - 80°C; 0.5 h;
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 556 - 559
反应条件
1: thionyl chloride 2: xylene; palladium / Hydrogenation.Isolierung ueber das Natriumhydrogensulfit-Addukt View Scheme
参考文献
Thuaud, Frederic; Kojima, Shuntaro; Hirai, Go; Oonuma, Kana; Tsuchiya, Ayako; Uchida, Takako; Tsuchimoto, Teruhisa; Sodeoka, Mikiko
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 9 p. 2771 - 2782
反应条件
thionyl chloride; chloroform und anschliessend mit Ammoniak und Behandlung des erhaltenen Amids mit Natriumhypochlorit-Loesung;
参考文献
Slotta; Heller
Chemische Berichte, 1930 , vol. 63, p. 3029,3043
反应条件
Novozym 435; acylase I from Aspergillus melleus; amano lipase AK from pseudomonas fluorescens; lipase from wheat germ; papaine in toluene
T=40°C; 48 h; Enzymatic reaction; Mechanism;
参考文献
Zysk, Malgorzata; Zadlo, Anna; Brodzka, Anna; Wisniewska, Catalina; Ostaszewski, Ryszard
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 102, p. 225 - 229
反应条件
hydrogenchloride; ethanol
参考文献
Lockett; Short
Journal of the Chemical Society, 1939 , p. 787,789
反应条件
tetrachloromethane; bromine
T=-10°C;
参考文献
Barnes; Kraft; Gordon
Journal of the American Chemical Society, 1949 , vol. 71, p. 3523,3527
反应条件
1: hydrogen chloride; ethanol
2: sodium; ethanol
3: pyridine; SOCl2
4: potassium cyanide; ethanol / Erhitzen des Reaktionsprodukts mit methanol. KOH
View Scheme
参考文献
Lockett; Short
Journal of the Chemical Society, 1939 , p. 787,789
反应条件
1: oxalyl chloride / diethyl ether
2: 0.74 g / diethyl ether / 3 h / -20 - 20 °C
View Scheme
参考文献
Ghosh, Somnath; Datta, Indira; Chakraborty, Rupak; Das, Tapas Kumar; Sengupta, Judhajit; Sarkar, Dipak Chandra
Tetrahedron, 1989 , vol. 45, # 5 p. 1441 - 1446
反应条件
sulfuric acid
2.5 h; RefluxInert atmosphere;
参考文献
Thuaud, Frederic; Kojima, Shuntaro; Hirai, Go; Oonuma, Kana; Tsuchiya, Ayako; Uchida, Takako; Tsuchimoto, Teruhisa; Sodeoka, Mikiko
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 9 p. 2771 - 2782
反应条件
Novozym 435; acylase I from Aspergillus melleus; amano lipase AK from pseudomonas fluorescens; lipase from wheat germ; papaine in toluene
T=40°C; 48 h; Enzymatic reaction; Mechanism;
参考文献
Zysk, Malgorzata; Zadlo, Anna; Brodzka, Anna; Wisniewska, Catalina; Ostaszewski, Ryszard
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 102, p. 225 - 229
