2,3-二氢-1H-苯并[e]茚-1-酮合成路线 （共 39 条）
反应条件
1: 67 percent / NBS, benzoyl peroxide / CCl4 / 2 h / Heating
2: 67 percent / CaCO3, H2O / dioxane / 10 h / Heating
3: 97 percent / PCC / CH2Cl2 / 1 h
4: 95 percent / toluene / 4 h / Heating
5: 64 percent / H2 / 10percent Pd/C / ethyl acetate / 3 h / 1137.7 Torr
6: 40 percent / n-Bu3SnH, AIBN / benzene / 5 h / Heating
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 95 percent / toluene / 4 h / Heating
2: 64 percent / H2 / 10percent Pd/C / ethyl acetate / 3 h / 1137.7 Torr
3: 40 percent / n-Bu3SnH, AIBN / benzene / 5 h / Heating
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 97 percent / PCC / CH2Cl2 / 1 h
2: 95 percent / toluene / 4 h / Heating
3: 64 percent / H2 / 10percent Pd/C / ethyl acetate / 3 h / 1137.7 Torr
4: 40 percent / n-Bu3SnH, AIBN / benzene / 5 h / Heating
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 94 percent / Et3N, CuI / (Ph3P)2PdCl2 / tetrahydrofuran / Ambient temperature
2: 89 percent / PCC / CH2Cl2 / 8 h
3: 84 percent / diethyl ether / 0.5 h / Ambient temperature
4: 97 percent / K2CO3 / methanol / 0.5 h / Ambient temperature
5: 90 percent / PCC / CH2Cl2 / 2 h
6: 5 percent / 1,4-cyclohexadiene / chlorobenzene / 8 h / 190 °C
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 64 percent / H2 / 10percent Pd/C / ethyl acetate / 3 h / 1137.7 Torr
2: 40 percent / n-Bu3SnH, AIBN / benzene / 5 h / Heating
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
反应条件
1.1: pyridine; piperidine; hydrogen / 3 h / 85 °C
1.2: 88 percent / Pd/C / ethyl acetate; methanol / 14 h / 20 °C / 836.06 Torr
2.1: 100 percent / phosphoric oxide; phosphoric acid / 0.67 h / 90 °C
View Scheme
参考文献
Kita; Higuchi; Yoshida; Iio; Kitagaki; Ueda; Akai; Fujioka
Journal of the American Chemical Society, 2001 , vol. 123, # 14 p. 3214 - 3222
反应条件
1: SnCl4; nitrobenzene
2: sulfur / 250 °C
View Scheme
参考文献
Arnold; Rondestvedt
Journal of the American Chemical Society, 1946 , vol. 68, p. 2176
反应条件
1: 89 percent / PCC / CH2Cl2 / 8 h
2: 84 percent / diethyl ether / 0.5 h / Ambient temperature
3: 97 percent / K2CO3 / methanol / 0.5 h / Ambient temperature
4: 90 percent / PCC / CH2Cl2 / 2 h
5: 5 percent / 1,4-cyclohexadiene / chlorobenzene / 8 h / 190 °C
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 84 percent / diethyl ether / 0.5 h / Ambient temperature
2: 97 percent / K2CO3 / methanol / 0.5 h / Ambient temperature
3: 90 percent / PCC / CH2Cl2 / 2 h
4: 5 percent / 1,4-cyclohexadiene / chlorobenzene / 8 h / 190 °C
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
反应条件
1: 90 percent / PCC / CH2Cl2 / 2 h
2: 5 percent / 1,4-cyclohexadiene / chlorobenzene / 8 h / 190 °C
View Scheme
参考文献
Grissom, Janet Wisniewski; Klingberg, Detlef; Meyenburg, Sabine; Stallman, Brenda L.
Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7876 - 7888
