4-羟基-4-(3-(三氟甲基)苯基)哌啶-1-羧酸叔丁酯合成路线 （共 3 条）
反应条件
hydrogenchloride in ethyl acetate T=20°C;
参考文献
Chen, Gang; Xia, Hongguang; Cai, Yu; Ma, Dawei; Yuan, Junying; Yuan, Chengye
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 1 p. 234 - 239
反应条件
1: in tetrahydrofuran
T=20°C;
2: With water; ammonium chloride in tetrahydrofuran
T=20°C; Saturated solution;
参考文献
Gruenenthal GmbH
Patent: US2009/264400 A1, 2009 ;
Location in patent: Page/Page column 97 ;
US 20090264400 A1
反应条件
triethylamine in dichloromethane
T=20°C; 18 h;
参考文献
sanofi-aventis
Patent: US2005/176722 A1, 2005 ;
Location in patent: Page/Page column 10 ;
