5-硝基-2-苯基巯基-苯甲酸合成路线 （共 11 条）
反应条件
1: oxalyl chloride; DMF / CH2Cl2 / 20 °C 2: 4.21 g / pyridine / CH2Cl2 / 20 °C View Scheme
参考文献
Parlow, John J.; Stevens, Anna M.; Stegeman, Roderick A.; Stallings, William C.; Kurumbail, Ravi G.; South, Michael S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4297 - 4312
反应条件
1: 70 percent / conc. H2SO4 / 100 - 105 °C 2: 80 percent / stannous chloride, conc. HCl / acetic acid / 5 h / Heating View Scheme
参考文献
Arur, P. V.; Kulkarni, Sheshgiri N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 1 p. 50 - 52
反应条件
1: oxalyl chloride; DMF / CH2Cl2 / 20 °C 2: 4.21 g / pyridine / CH2Cl2 / 20 °C 3: 75 percent / Fe; glacial AcOH / 80 °C View Scheme
参考文献
Parlow, John J.; Stevens, Anna M.; Stegeman, Roderick A.; Stallings, William C.; Kurumbail, Ravi G.; South, Michael S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4297 - 4312
反应条件
potassium carbonate in water
T=150°C; 2 h;
参考文献
Lan, Cong; Xia, Zhi-Ning; Li, Zheng-Hua; Liang, Rong-Hui
Journal of Chemical Research, 2012 , vol. 36, # 12 p. 726 - 728
反应条件
copper(I) oxide; copper; potassium carbonate in 2-ethoxy-ethanol
T=130°C; 4 h;
参考文献
Liu, Shuanglong; Pestano, John Paul C.; Wolf, Christian
Synthesis, 2007 , # 22 p. 3519 - 3527
反应条件
triethylamine in tetrahydrofuran
20 h; Heating;
参考文献
Parlow, John J.; Stevens, Anna M.; Stegeman, Roderick A.; Stallings, William C.; Kurumbail, Ravi G.; South, Michael S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4297 - 4312
反应条件
potassium hydroxide; copper
Heating;
参考文献
Valenta; Bartl; Dlabac; et al.
Collection of Czechoslovak Chemical Communications, 1976 , vol. 41, # 12 p. 3607 - 3627
反应条件
1: concentrated sulfuric acid
2: nitric acid; sulfuric acid
3: acetic acid; tin (II)-chloride; hydrogen chloride
4: acetic acid
View Scheme
参考文献
Amstutz; Neumoyer
Journal of the American Chemical Society, 1947 , vol. 69, p. 1925,1928
反应条件
1: NaBH4 / tetrahydrofuran
2: SOCl2 / benzene
3: (i) DMF, (ii) aq. H2SO4, AcOH
View Scheme
参考文献
Sindelar,K. et al.
Collection of Czechoslovak Chemical Communications, 1975 , vol. 40, p. 2650 - 2666
反应条件
hydrogenchloride; iron
1) water, 90-95 deg C, 2) methanol, reflux, 3-4 h;
参考文献
Arur, P. V.; Kulkarni, Sheshgiri N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 1 p. 50 - 52
