3-苄氧基-4-甲氧基苯甲醛合成路线 （共 78 条）
反应条件
1: 73 percent / 1.) n-butyl-lithium / tetrahydrofuran; hexane / 1.) 20 deg C, 90 min, 2.) 20 deg C, 18 h
2: 71 percent / pyridine / 22 h
3: 97 percent / H2 / 10percent palladium on carbon / ethyl acetate / 16 h / 20 °C
4: 24 percent / potassium carbonate, potassium iodide, 18-crown-6 / acetone / 22 h / Heating
5: H2 / Lindlar catalyst / ethyl acetate / 0.33 h / 20 °C
6: 40 mg / 1.25 h / 150 °C
7: 90 percent / aqueous 10percent sodium hydroxide, ethanol / 1 h / 85 °C
View Scheme
参考文献
Crombie, Leslie; Crombie, W. Mary L.; Jamieson, Sally V.
Tetrahedron Letters, 1980 , vol. 21, # 37 p. 3607 - 3610
反应条件
1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride in tetrahydrofuran
T=0 - 5°C; 0.5 h;
2: 4-methoxy-3-(phenylmethoxy)benzaldehyde in tetrahydrofuran
T=0 - 20°C; 0.75 h;
参考文献
Park, Ju-Eun; Lee, Juyeun; Seo, Seung-Yong; Shin, Dongyun
Tetrahedron Letters, 2014 , vol. 55, # 4 p. 818 - 820
反应条件
1: (i) K, tBuOH, (heating), (ii) /BRN= 385737/, NaOAc
2: (i) aq. KOH, (ii) /BRN= 635994/, K2CO3
View Scheme
参考文献
Cooke,R.G.; Owen,W.R.
Australian Journal of Chemistry, 1962 , vol. 15, p. 486 - 491
反应条件
1: 81 percent
2: 60 percent / H2, AcOH / 10 percent Pd/C / CHCl3; ethanol / 4 h / 2585.7 Torr
View Scheme
参考文献
Morais, Anselmo A.; Fo, Raimundo Braz; Gottlieb, Otto R.
Phytochemistry (Elsevier), 1985 , vol. 24, # 12 p. 3023 - 3028
反应条件
1: ammonium acetate; acetic acid / |Reflux
2: lithium aluminium tetrahydride
3: acetic acid; trifluoroacetic acid
View Scheme
参考文献
Liu, Chunyi; Chen, Zhengping; Li, Xiaomin; Tang, Jie; Qin, Xiaofeng
Chirality, 2013 , vol. 25, # 4 p. 215 - 223
反应条件
iodine; silver trifluoroacetate in chloroform
1 h; Ambient temperature;
参考文献
Hewgill, Frank R.; Pass, Michael C.
Australian Journal of Chemistry, 1985 , vol. 38, # 4 p. 537 - 554
反应条件
1: 73 percent / NH4OAc, HOAc / Heating
2: 1.) NaN(SiMe3)2 / 1.) THF
3: 72 percent / H2 / Raney-Nickel / ethyl acetate; ethanol / 20 h / 22 °C / 2250.2 Torr
4: 60 percent / NaH / tetrahydrofuran / Heating
View Scheme
参考文献
Mulzer, Johann; Zuhse, Ralf; Schmiechen, Ralph
Angewandte Chemie, 1992 , vol. 104, # 7 p. 914 - 915
反应条件
1: 83 percent / sodium borohydride / ethanol / 0.5 h
2: 88 percent / PBr3 / benzene / 0.5 h / 5 °C
3: 50 percent / n-butyl lithium / tetrahydrofuran / 3 h / -30 °C
4: mercuric chloride / methanol; tetrahydrofuran / 24 h / 130 °C
5: trifluoroacetic acid / 3 h / Ambient temperature
View Scheme
参考文献
Annapurna, G. S.; Deshpande, V. H.
Synthetic Communications, 1983 , vol. 13, # 13 p. 1075 - 1082
反应条件
potassium hydroxide in methanol; N,N-dimethyl-formamide
T=-10°C; 2.5 h; Inert atmosphere;
参考文献
Schrittwieser, Joerg H.; Resch, Verena; Wallner, Silvia; Lienhart, Wolf-Dieter; Sattler, Johann H.; Resch, Jasmin; MacHeroux, Peter; Kroutil, Wolfgang
Journal of Organic Chemistry, 2011 , vol. 76, # 16 p. 6703 - 6714
反应条件
1: NaBH4
2: SOCl2
4: HCl / ethanol
View Scheme
参考文献
Bhandari, Prabha; Crombie, Leslie; Daniels, Peter; Holden, Ian; Bruggen, Nicholas Van; Whiting, Donald A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 7 p. 839 - 850
