(R)-(+)-3-甲基戊二酸甲酯合成路线 （共 24 条）
反应条件
pyridine; oxygen; ozone in methanol; dichloromethane T=0°C;
参考文献
Russian Journal of Organic Chemistry, , vol. 49, # 1 p. 42 - 45
Zh. Org. Khim., , vol. 49, # 1 p. 52 - 55,4
反应条件
1: 6.11 g / diethyl ether / Ambient temperature 2: 99 percent / H2 / 10 percent Pd/C / ethyl acetate / 96 h / 760 Torr / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 1 p. 142 - 146
反应条件
1: diethyl ether / 0.17 h / 25 °C 2: formic acid / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 42, # 11 p. 2919 - 2929
反应条件
1: 96 percent / triphenyltin hydride / toluene / Heating 2: formic acid / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 42, # 11 p. 2919 - 2929
反应条件
1: 91 percent / H2 / 10percent palladium on active carbon / 65 °C / 3040 Torr 2: 64 percent / pig liver esterase, 10percent sodium hydroxide View Scheme
参考文献
Tetrahedron, , vol. 44, # 5 p. 1477 - 1488
反应条件
1: 93 percent / NaCl / dimethylsulfoxide; H2O / 4.5 h / Heating 2: 98 percent / pig liver esterase, (0.1 M phosphate buffer) / 23 °C View Scheme
参考文献
Tetrahedron, , vol. 44, # 1 p. 119 - 126
反应条件
acetone; CD Zerlegen des auskrystallisierenden Cinchonidinsalzes der (+) (R)-Form mit verd. HCl;
参考文献
Arkiv foer Kemi, , vol. 25A, # 10 p. 3
Arkiv foer Kemi, , vol. 26A, # 1 p. 4
反应条件
formic acid 1.5 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 42, # 11 p. 2919 - 2929
反应条件
1: propionic acid; sodium methylate / Electrolysis 2: aq.-ethanolic KOH-solution View Scheme
参考文献
Staellberg; Stenhagen
Arkiv foer Kemi, 1950 , vol. 2, p. 95,102
反应条件
potassium hydroxide; acetic anhydride Multistep reaction; Product distribution;
参考文献
Rossi, Renzo; Carpita, Adriano; Chini, Marco
Tetrahedron, 1985 , vol. 41, # 3 p. 627 - 634
