1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
dimethyl-disulfide; hydrogen; sulfided NiMo-Al2O3 in n-heptane T=349.9°C; P=52504.2 Torr; 2 h; effect of H2S partial pressure of title compound; Product distribution;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 100, # 11 p. 807 - 814
反应条件
hydrogen; nickel T=210°C; P=7600 Torr; or Ru/C, 100 atm, 150 deg C; Equilibrium constant;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 63, # 11 p. 3167 - 3174
反应条件
1: Ac2O / 1 h / 60 °C 2: 98 percent / NaIO4 / methanol / 6 h / 20 °C 3: 60 percent / TFAA; BF3*Et2O / benzene / 2 h / 20 °C 4: 98 percent / NaBH4; NiCl2*6H2O / methanol; tetrahydrofuran / 1.5 h / 20 °C 5: 93 percent / 10 percent NaOH / ethanol / 6 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 47, # 9 p. 1269 - 1275
反应条件
1: 98 percent / NaIO4 / methanol / 6 h / 20 °C 2: 60 percent / TFAA; BF3*Et2O / benzene / 2 h / 20 °C 3: 98 percent / NaBH4; NiCl2*6H2O / methanol; tetrahydrofuran / 1.5 h / 20 °C 4: 93 percent / 10 percent NaOH / ethanol / 6 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 47, # 9 p. 1269 - 1275
反应条件
1: 60 percent / TFAA; BF3*Et2O / benzene / 2 h / 20 °C 2: 98 percent / NaBH4; NiCl2*6H2O / methanol; tetrahydrofuran / 1.5 h / 20 °C 3: 93 percent / 10 percent NaOH / ethanol / 6 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 47, # 9 p. 1269 - 1275
反应条件
1: 98 percent / NaBH4; NiCl2*6H2O / methanol; tetrahydrofuran / 1.5 h / 20 °C 2: 93 percent / 10 percent NaOH / ethanol / 6 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 47, # 9 p. 1269 - 1275
反应条件
1: 44 percent / 1,1,2-trichloro-1,2,2-trifluoro-ethane / 36 h / 135 °C 2: 86.9 percent / 650 °C / 0.01 Torr View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 20 p. 1087 - 1088
反应条件
1: 95 percent / pyridine-borane / ethanol / below 5 deg C 2: 55 percent / CF3COOH / 15 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 6 p. 1615 - 1623
反应条件
hydrogen; molybdenium carbide in 1,2,3,4-tetrahydro-naphthalene T=369.9°C; P=23251.8 Torr; 60 h; investigation of hydrogenation and hydrodenitrogenation; different catalysts; Product distributionMechanism;
参考文献
Journal of Physical Chemistry, , vol. 99, # 44 p. 16365 - 16372
反应条件
1: 1.) MeLi, t-BuLi / 1.) a) hexane, THF, -78 deg C, 30 min, b) -15 deg C, 3 h, 2.) RT, overnight 2: 85 percent / conc. HCl / 14 h / 105 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 23 p. 5574 - 5580
