1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
in N,N-dimethyl acetamide T=0 - 20°C;
参考文献
Flipo, Marion; Willand, Nicolas; Lecat-Guillet, Nathalie; Hounsou, Candide; Desroses, Matthieu; Leroux, Florence; Lens, Zoe; Villeret, Vincent; Wohlkoenig, Alexandre; Wintjens, Rene; Christophe, Thierry; Kyoung Jeon, Hee; Locht, Camille; Brodin, Priscille; Baulard, Alain R; Deprez, Benoit
Journal of Medicinal Chemistry, 2012 , vol. 55, # 14 p. 6391 - 6402
反应条件
hydrogen; nickel-tungsten T=350°C; P=63755.1 - 108759 Torr; 8 h; other temperature; Product distribution;
参考文献
Cerny, Mirko; Trka, Antonin
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 6 p. 1749 - 1758
反应条件
hydrogen sulfide; hydrogen; nickel-tungsten T=350°C; P=13876.1 - 108759 Torr; 8 h; Product distribution;
参考文献
Cerny, Mirko; Trka, Antonin
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 6 p. 1749 - 1758
反应条件
1: 63 percent / HNO3; H2SO4 / 0 - 5 °C 2: K2CO3 / dimethylformamide / 20 °C 3: H2 / Pd/C / methanol / 20 °C / 760 Torr View Scheme
参考文献
Westaway, Susan M.; Chung, Ying-Kit; Davis, John B.; Holland, Vicky; Jerman, Jeffrey C.; Medhurst, Stephen J.; Rami, Harshad K.; Stemp, Geoffrey; Stevens, Alexander J.; Thompson, Mervyn; Winborn, Kim Y.; Wright, James
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4533 - 4536
参考文献
Hoffmann; Koenigs
Chemische Berichte, 1883 , vol. 16, p. 735
反应条件
oxygen in acetonitrile T=100°C; P=3750.38 Torr; 4.5 h; AutoclaveIrradiation;
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 3 p. 657 - 660
反应条件
in tetrahydrofuran 19 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 41, # 21 p. 4727 - 4738
反应条件
molybdenum(VI) sulfide T=430 - 500°C; Hydrogenation;
参考文献
Jeru; Ssachnowskaja; Pytschko
Zhurnal Obshchei Khimii, 1938 , vol. 8, p. 1563,1569
Chem. Zentralbl., 1939 , vol. 110, # I p. 4952
反应条件
hydrogen; aluminum oxide; nickel molybdenum in decane T=349.9°C; P=52504.2 Torr;
参考文献
Perot, G.; Brunet, S.; Canaff, C.; Toulhoat, H.
Bulletin des Societes Chimiques Belges, 1987 , vol. 96, # 11-12 p. 865 - 870
反应条件
2-amino-1,3-diethylbenzene; hydrogen sulfide; hydrogen; zirconium oxide; molybdenum in decane T=340°C; P=52504.2 Torr; other catalysts; Rate constantMechanism;
参考文献
Moreau, C.; Bekakra, L.; Geneste, P.; Olive, J. L.; Duchet, J. C.; et al.
Bulletin des Societes Chimiques Belges, 1991 , vol. 100, # 11 p. 841 - 848
