1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
hydrogen; nickel T=210°C; P=7600 Torr; or 200 deg C, or Ru/C, 100 or 10 atm, 150 deg C, and competitive hydrogenation with 1,2,3,4-tetrahydroisoquinoline; Equilibrium constant;
参考文献
Okazaki, Hiroshi; Onishi, Kiyotaka; Soeda, Mahito; Ikefuji, Yoshio; Tamura, Ryuji; Mochida, Isao
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 11 p. 3167 - 3174
反应条件
hydrogen; nickel T=210°C; P=7600 Torr; or 200 deg C, or Ru/C, 100 or 10 atm, 150 deg C, and competitive hydrogenation with 1,2,3,4-tetrahydroisoquinoline; Rate constant;
参考文献
Okazaki, Hiroshi; Onishi, Kiyotaka; Soeda, Mahito; Ikefuji, Yoshio; Tamura, Ryuji; Mochida, Isao
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 11 p. 3167 - 3174
反应条件
hydrogen; nickel T=200°C; P=7600 Torr; 2 h; other reaction time; Product distribution;
参考文献
Okazaki, Hiroshi; Onishi, Kiyotaka; Soeda, Mahito; Ikefuji, Yoshio; Tamura, Ryuji; Mochida, Isao
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 11 p. 3167 - 3174
反应条件
T=230 - 240°C; im Rohr;
参考文献
Bamberger; Williamson
Chemische Berichte, 1894 , vol. 27, p. 1470
Full Text Show Details
Bamberger; Lengfeld
Chemische Berichte, 1890 , vol. 23, p. 1142
反应条件
1: sodium carbonate 2: N-bromosuccinmide / acetonitrile / 3 h / 0 - 20 °C View Scheme
参考文献
Shao, Jingyin; Ji, Shaomin; Li, Xiaolian; Zhao, Jianzhang; Zhou, Fuke; Guo, Huimin
European Journal of Organic Chemistry, 2011 , # 30 p. 6100 - 6109
反应条件
C18H32ClIrOP2S; sodium t-butanolate in para-xylene T=120°C; 12 h; Inert atmosphereSchlenk techniqueGloveboxSealed tube;
参考文献
Yao, Wubing; Zhang, Yuxuan; Jia, Xiangqing; Huang, Zheng
Angewandte Chemie - International Edition, 2014 , vol. 53, # 5 p. 1390 - 1394
Angew. Chem., 2014 , vol. 126, # 5 p. 1414 - 1418
反应条件
O-(2,4,6-trimethylbenzenesulfonyl)hydroxylamine in dichloromethane T=25°C; 1 h; Yield given;
参考文献
Letcher, Roy M.; Choi, Michael C. K.; Acheson, R. Morrin; Prince, Richard J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , p. 501 - 504
反应条件
hydrogen fluoride; dihydrogen peroxide; SbF5 T=-20°C; 0.166667 h;
参考文献
Tetrahedron Letters, , vol. 27, # 38 p. 4565 - 4568
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 50 °C / |Cooling with ice; |Inert atmosphere 2: N-bromosuccinmide / N,N-dimethyl-formamide / 2.5 h / 20 °C / |Cooling with ice; |Inert atmosphere View Scheme
参考文献
Fukaya, Takayuki; Kodo, Toru; Ishiyama, Takeo; Nishikawa, Hiroyuki; Baba, Satoko; Masumoto, Shuji
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 5 p. 1257 - 1267
反应条件
1: pyridine / dichloromethane / 1 h / 0 - 25 °C 2: nitric acid; acetic anhydride / 4 h / -10 - 25 °C View Scheme
参考文献
Cordeiro, Alessandra; Shaw, Julian; O'Brien, John; Blanco, Fernando; Rozas, Isabel
European Journal of Organic Chemistry, 2011 , # 8 p. 1504 - 1513
