1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
in N,N-dimethyl-formamide
T=0 - 5°C; 5 h;
参考文献
Ganguly, Swastika; Murugesan
Journal of the Indian Chemical Society, 2010 , vol. 87, # 7 p. 879 - 885
参考文献
Bahner et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 4198
反应条件
potassium carbonate
T=60°C; 18 h;
参考文献
Zachariasse, Klaas A.; Druzhinin, Sergey I.; Bosch, Wilfried; Machinek, Reinhard
Journal of the American Chemical Society, 2004 , vol. 126, # 6 p. 1705 - 1715
反应条件
sodium tungstate; dihydrogen peroxide
12 h; Ambient temperature;
参考文献
Lion, C.; Hedayatullah, M.; Bauer, P.; Boukou-Poba, J. P.; Charvy, C.; et al.
Bulletin des Societes Chimiques Belges, 1991 , vol. 100, # 8 p. 617 - 621
反应条件
dihydrogen peroxide; sodium tungstate in methanol
24 h; Ambient temperature;
参考文献
Murahashi, Shun-Ichi; Oda, Tetsuya; Sugahara, Toshiaki; Masui, Yoshiyuki
Journal of Organic Chemistry, 1990 , vol. 55, # 6 p. 1744 - 1749
反应条件
dihydrogen peroxide; copper(II) oxide in methanol
24 h; Ambient temperatureother catalysts, other solvents, other times investigated; Product distributionMechanism;
参考文献
Murahashi, Shun-Ichi; Oda, Tetsuya; Sugahara, Toshiaki; Masui, Yoshiyuki
Journal of Organic Chemistry, 1990 , vol. 55, # 6 p. 1744 - 1749
反应条件
1: 1,2,3,4-tetrahydro-quinoline With triethylamine in dichloromethane
T=0°C; 0.0833333 h; Inert atmosphere;
2: 6-bromopiperonylic chloride in dichloromethane; toluene
T=0 - 20°C; Inert atmosphere;
参考文献
De, Subhadip; Ghosh, Santanu; Bhunia, Subhajit; Sheikh, Javeed Ahmad; Bisai, Alakesh
Organic Letters, 2012 , vol. 14, # 17 p. 4466 - 4469
反应条件
1: 1,2,3,4-tetrahydro-quinoline With triethylamine in dichloromethane
T=0°C; 0.0833333 h; Inert atmosphere;
2: 2-bromo-4,5-dimethoxybenzoic acid chloride in dichloromethane; toluene
T=0 - 20°C; Inert atmosphere;
参考文献
De, Subhadip; Ghosh, Santanu; Bhunia, Subhajit; Sheikh, Javeed Ahmad; Bisai, Alakesh
Organic Letters, 2012 , vol. 14, # 17 p. 4466 - 4469
参考文献
PHARMACIA CORPORATION
Patent: WO2003/99769 A1, 2003 ;
Location in patent: Page 52 ;
反应条件
aluminium trichloride in dichloromethane; n-butyl chloride
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4251659 A1, 1981 ;
