1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
in chloroform
T=20°C; 2 h;
参考文献
Zelenin, A. E.; Chkanikov, N. D.; Umnov, A. M.; Kolomiets, A. F.; Fokin, A. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, p. 1890 - 1894
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , p. 2074 - 2080
参考文献
Cromwell et al.
Journal of the American Chemical Society, 1944 , vol. 66, p. 134
参考文献
Holliman; Mann
Journal of the Chemical Society, 1945 , p. 45,47
反应条件
1: With potassium carbonate in N,N-dimethyl-formamide
T=60°C; 4 h;
2: With sodium hydroxide in dichloromethane; water
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2006/62224 A1, 2006 ;
Location in patent: Page/Page column 74 ;
反应条件
orthoformic acid triethyl ester
参考文献
Farbw. Hoechst
Patent: DE834104 , 1951 ;
DRP/DRBP Org.Chem.
参考文献
GLAXO GROUP LIMITED; GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O.
Patent: WO2007/54296 A1, 2007 ;
Location in patent: Page/Page column 67 ;
反应条件
in n-heptane; 1,2-dichloro-benzene
参考文献
McDougall, Mark; Dwight, Stephen
Patent: US2010/233710 A1, 2010 ;
反应条件
potassium carbonate in acetonitrile
T=20°C; 24 h;
参考文献
Alcaide, Benito; Almendros, Pedro; Alonso, Jose M.; Aly, Moustafa F.
Organic Letters, 2001 , vol. 3, # 23 p. 3781 - 3784
反应条件
in triethylamine
T=80°C; 1 h;
参考文献
Abdrakhmanov, I. V.; Mustafin, A. G.; Tolstikov, G. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, p. 1657 - 1661
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 8 p. 1852 - 1857
反应条件
tetrakis(triphenylphosphine) palladium(0); triethylamine; tin(ll) chloride in tetrahydrofuran
T=50°C; 69 h;
参考文献
Masuyama, Yoshiro; Kagawa, Masaaki; Kurusu, Yasuhiko
Chemistry Letters, 1995 , # 12 p. 1121 - 1122
