1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
1: ZnCl2 / xylene / 130 °C
View Scheme
参考文献
Abdrakhmanov, I. V.; Mustafin, A. G.; Tolstikov, G. A.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1988 , vol. 37, p. 1657 - 1661
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1988 , # 8 p. 1852 - 1857
参考文献
Okimoto, Mitsuhiro; Yoshida, Takashi; Hoshi, Masayuki; Hattori, Kazuyuki; Komata, Masashi; Numata, Kaori; Tomozawa, Kenta
Australian Journal of Chemistry, 2007 , vol. 60, # 4 p. 236 - 242
反应条件
triethylamine in tetrahydrofuran
T=0 - 20°C;
参考文献
ATTENUON, LLC; CHANGCHUN DISCOVERY SCIENCES, LTD.
Patent: WO2006/89298 A2, 2006 ;
Location in patent: Page/Page column 101-102 ;
反应条件
C21H38AuClNP*C24BF20(1-)*K(1+) in benzene-d6
T=70°C; Markovnikov hydroamination; 9 h; Inert atmosphere;
参考文献
Xiaoming, Zeng; Soleilhavoup, Michele; Bertrand, Guy
Organic Letters, 2009 , vol. 11, # 15 p. 3166 - 3169
反应条件
1: 1,2,3,4-tetrahydro-quinoline With sodium hydride in tetrahydrofuran; mineral oil
Inert atmosphere;
2: prenyl bromide in tetrahydrofuran; mineral oil
14 h; Inert atmosphereReflux;
参考文献
Gansaeuer, Andreas; Behlendorf, Maike; Von Laufenberg, Daniel; Fleckhaus, Andre; Kube, Christian; Sadasivam, Dhandapani V.; Flowers II, Robert A.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 19 p. 4739 - 4742
反应条件
sodium carbonate in acetonitrile
Ambient temperature;
参考文献
Katayama, Hajime; Tachikawa, Yoshio; Takatsu, Noriyuki; Kato, Akira
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 7 p. 2220 - 2233
反应条件
1: sodium carbonate / acetonitrile / Ambient temperature
2: 48 percent / boron trifluoride etherate / 2 h / 140 °C
View Scheme
参考文献
Katayama, Hajime; Tachikawa, Yoshio; Takatsu, Noriyuki; Kato, Akira
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 7 p. 2220 - 2233
反应条件
1: sodium carbonate / acetonitrile / Ambient temperature
2: 6.9 percent / boron trifluoride etherate / 2 h / 140 °C
View Scheme
参考文献
Katayama, Hajime; Tachikawa, Yoshio; Takatsu, Noriyuki; Kato, Akira
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 7 p. 2220 - 2233
反应条件
1: sodium carbonate / acetonitrile / Ambient temperature
2: 48 percent / boron trifluoride etherate / 2 h / 140 °C
3: sodium cyanoborohydride / acetic acid; acetonitrile / 2 h
View Scheme
参考文献
Katayama, Hajime; Tachikawa, Yoshio; Takatsu, Noriyuki; Kato, Akira
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 7 p. 2220 - 2233
反应条件
1: sodium carbonate / acetonitrile / Ambient temperature
2: 48 percent / boron trifluoride etherate / 2 h / 140 °C
3: pyridine / 4.5 h / Ambient temperature
4: 83 percent / ozonized air / methanol / -40 °C
View Scheme
参考文献
Katayama, Hajime; Tachikawa, Yoshio; Takatsu, Noriyuki; Kato, Akira
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 7 p. 2220 - 2233
