1,2,3,4-四氢喹啉合成路线 （共 372 条）
反应条件
sodium chloride in diethyl ether
参考文献
PROMEGA CORPORATION; CORONA, Cesear; KLAUBERT, Dieter; MCDOUGALL, Mark
Patent: WO2011/26085 A2, 2011 ;
Location in patent: Page/Page column 53 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=0 - 50°C; 6 h;
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1719761 A1, 2006 ;
Location in patent: Page/Page column 28 ;
反应条件
1: triethylamine / diethyl ether / 0 - 20 °C
2: chlorosulfonic acid / tetrachloromethane / 2 h / 0 - 20 °C / Inert atmosphere
View Scheme
参考文献
NORTH CAROLINA STATE UNIVERSITY; DEITERS, Alexander; YOUNG, Douglas, D.
Patent: WO2011/91209 A1, 2011 ;
反应条件
in N,N-dimethyl-formamide
T=60°C; 0.166667 h; Sonication;
参考文献
Deligeorgiev, Todor; Lesev, Nedyalko; Kaloyanova, Stefka
Dyes and Pigments, 2011 , vol. 91, # 1 p. 74 - 78
参考文献
Ohki
Yakugaku Zasshi, 1950 , vol. 70, p. 92,98
Chem.Abstr., 1950 , p. 5867
反应条件
1: sodium acetate; aqueous acetone
2: aluminium chloride
3: water; sulfuric acid / bei der elektrochemischen Reduktion an Blei-Kathoden.
View Scheme
参考文献
Sugimoto
Yakugaku Zasshi, 1944 , vol. 64, # 7 p. 4
Chem.Abstr., 1952 , p. 114
反应条件
1: 60 percent / N-bromosuccinimide / CCl4 / 3 h / 20 °C
2: 60 percent / dimethylformamide / 16 h / Heating
View Scheme
参考文献
BIOENERGENIX; MCCALL, John, M.; ROMERO, Donna, L.
Patent: WO2012/94462 A2, 2012 ;
WO 2012/094462 A2
反应条件
boron trichloride; potassium carbonate in methanol; dichloromethane; toluene
参考文献
Shionogi and Co., Ltd.
Patent: US4774331 A1, 1988 ;
反应条件
Yield given. Multistep reaction;
参考文献
Adachi, Makoto; Sugasawa, Tsutomu
Synthetic Communications, 1990 , vol. 20, # 1 p. 71 - 84
反应条件
sulfuric acid
T=60°C; 0.5 h; other reaction times; Product distributionRate constant;
参考文献
Okhrimenko, Z. A.; Chekhuta, V. G.; Kachurin, O. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 4 p. 409 - 412
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 4 p. 506 - 509
